Pentylenetetrazole (PTZ)-induced seizure is one of the gold standard mouse models for
rapid evaluation of novel anticonvulsants. Synchronically, PTZ induced kindling in mice is …

Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial
number of patients facing drug-resistant epilepsy. This comprehensive review explores …

Epilepsy affects around 50 million people across the globe and is the third most common
chronic brain disorder. It is a non-communicable disease of the brain that affects people of …

Stress, which refers to a combination of physiological, neuroendocrine, behavioral, and
emotional responses to novel or threatening stimuli, is essentially a defensive adaptation …

Ethnopharmacological relevance Anoectochilus roxburghii (A. roxburghii) is a precious herb
and folk medicine in many Asian countries. It has been used traditionally to treat diabetes …

Epilepsy, a chronic neurological condition, impacts millions of individuals globally and
remains a significant contributor to both illness and mortality. Available antiepileptic drugs …

Parkia biglobosa (Jacq.) R. Br.(Fabaceae) is a widely distributed tree, used in traditional
medicine to treat amebiasis, hookworm infection, ascariasis, asthma, sterility, dental pain …

Introduction Epilepsy is a highly prevalent neurological disease whose treatment has always
been challenging. Hence, it is crucial to explore the molecular mechanisms underlying …

Pentylenetetrazole (PTZ)-induced kindling is an animal model for studying human temporal
lobe epilepsy (TLE), which is characterized by alterations of hippocampal neurons and …

Epilepsy is a chronic neurological condition in which inflammation and oxidative stress play
a key role in the pathogenesis. Recently, several studies have suggested that Royal Jelly …