Anatomy and neurophysiology of cough: CHEST Guideline and Expert Panel report

BJ Canning, AB Chang, DC Bolser, JA Smith… - Chest, 2014 - Elsevier
Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive
myelinated sensory nerves play essential roles in regulating cough. These vagal sensory …

Pharmacology and therapeutics of bronchodilators revisited

MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - ASPET
Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …

ERS guidelines on the diagnosis and treatment of chronic cough in adults and children

AH Morice, E Millqvist, K Bieksiene… - European …, 2020 - Eur Respiratory Soc
These guidelines incorporate the recent advances in chronic cough pathophysiology,
diagnosis and treatment. The concept of cough hypersensitivity has allowed an umbrella …

P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study

R Abdulqawi, R Dockry, K Holt, G Layton, BG McCarthy… - The Lancet, 2015 - thelancet.com
Background Preclinical studies suggest that P2X3 receptors are expressed by airway vagal
afferent nerves and contribute to the hypersensitisation of sensory neurons. P2X3 receptors …

Cough and the transmission of tuberculosis

RD Turner, GH Bothamley - The Journal of infectious diseases, 2015 - academic.oup.com
Cough is a predominant feature of respiratory infection and, in tuberculosis, is of prime
importance for transmitting infection. Tuberculosis is transmitted by the air, yet the process …

Global physiology and pathophysiology of cough: part 1: cough phenomenology–CHEST guideline and expert panel report

KK Lee, PW Davenport, JA Smith, RS Irwin… - Chest, 2021 - Elsevier
The purpose of this state-of-the-art review is to update the American College of Chest
Physicians 2006 guideline on global physiology and pathophysiology of cough. A review of …

[HTML][HTML] Clinical practice guidelines for diagnosis and management of cough—Chinese Thoracic Society (CTS) Asthma Consortium

K Lai, H Shen, X Zhou, Z Qiu, S Cai… - Journal of Thoracic …, 2018 - ncbi.nlm.nih.gov
Cough is the most common symptom in respiratory specialist clinics of tertiary hospitals and
outpatient clinics of primary health care facilities. In China, patients with chronic cough …

Comprehensive evidence-based review on European antitussives

A Morice, P Kardos - BMJ Open Respiratory Research, 2016 - bmjopenrespres.bmj.com
Acute cough caused by viral respiratory tract infections is probably the most common illness
to afflict mankind. Despite the widespread but ineffective prescribing of antibiotics, there is …

P2X3-receptor antagonists as potential antitussives: summary of current clinical trials in chronic cough

PV Dicpinigaitis, LP McGarvey, BJ Canning - Lung, 2020 - Springer
Cough is among the most common complaints for which patients worldwide seek medical
attention. In a majority of patients with chronic cough (defined as cough of greater than 8 …

Upper respiratory tract infection-associated acute cough and the urge to cough: New insights for clinical practice

V Murgia, S Manti, A Licari, M De Filippo… - Pediatric allergy …, 2020 - liebertpub.com
Upper respiratory tract infection (URTI)-associated acute cough is the most common
symptom both in children and adults worldwide and causes economic and social problems …