Obesity and cancer risk: Emerging biological mechanisms and perspectives

KI Avgerinos, N Spyrou, CS Mantzoros, M Dalamaga - Metabolism, 2019 - Elsevier
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Obesity, inflammation, and cancer

T Deng, CJ Lyon, S Bergin, MA Caligiuri… - Annual Review of …, 2016 - annualreviews.org
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including cancer, and is increasingly recognized as a growing cause of preventable cancer …

Associations between aspirin use and the risk of cancers: a meta-analysis of observational studies

Y Qiao, T Yang, Y Gan, W Li, C Wang, Y Gong, Z Lu - BMC cancer, 2018 - Springer
Background Epidemiological studies have clarified the potential associations between
regular aspirin use and cancers. However, it remains controversial on whether aspirin use …

Aspirin use and risk of breast cancer: a meta-analysis of observational studies from 1989 to 2019

S Ma, C Guo, C Sun, T Han, H Zhang, G Qu, Y Jiang… - Clinical Breast …, 2021 - Elsevier
Background Some evidence shows that aspirin can reduce the morbidity and mortality of
different cancers, including breast cancer. Aspirin has become a new focus of cancer …

Obese adipose tissue as a driver of breast cancer growth and development: update and emerging evidence

P Bhardwaj, KA Brown - Frontiers in Oncology, 2021 - frontiersin.org
Obesity is an established risk factor for breast cancer growth and progression. A number of
advances have been made in recent years revealing new insights into this link. Early events …

Adipose tissue macrophages as a therapeutic target in obesity‐associated diseases

AA Herrada, A Olate‐Briones, A Rojas, C Liu… - Obesity …, 2021 - Wiley Online Library
Obesity is an increasing problem in developed and developing countries. Individuals with
obesity have a higher risk of several diseases, such as cardiovascular disease, increased …

Relations of visceral and abdominal subcutaneous adipose tissue, body mass index, and waist circumference to serum concentrations of parameters of chronic …

I Schlecht, B Fischer, G Behrens, MF Leitzmann - Obesity facts, 2016 - karger.com
Background: Different measures of body fat composition may vary in their relations to
parameters of chronic inflammation. Methods: We assessed the relations of visceral (VAT) …

Regular and low-dose aspirin, other non-steroidal anti-inflammatory medications and prospective risk of HER2-defined breast cancer: the California Teachers Study

CA Clarke, AJ Canchola, LM Moy, SL Neuhausen… - Breast Cancer …, 2017 - Springer
Background Regular users of aspirin may have reduced risk of breast cancer. Few studies
have addressed whether risk reduction pertains to specific breast cancer subtypes defined …

Excess body weight and postmenopausal breast cancer: Emerging molecular mechanisms and perspectives.

D Nahmias-Blank, O Maimon, A Meirovitz… - Seminars in Cancer …, 2023 - Elsevier
Postmenopausal, obese women have a significantly higher risk of developing estrogen
receptor-positive (ER+) breast tumors, that are resistant to therapies and are associated with …

Current perspectives of molecular pathways involved in chronic inflammation-mediated breast cancer

S Suman, PK Sharma, G Rai, S Mishra, D Arora… - Biochemical and …, 2016 - Elsevier
Inflammation has multifaceted role in cancer progression including initiation, promotion and
invasion by affecting the immune surveillance and associated signaling pathways …