Super-resolution microscopy demystified

L Schermelleh, A Ferrand, T Huser, C Eggeling… - Nature cell …, 2019 - nature.com
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

Visualizing and discovering cellular structures with super-resolution microscopy

YM Sigal, R Zhou, X Zhuang - Science, 2018 - science.org
Super-resolution microscopy has overcome a long-held resolution barrier—the diffraction
limit—in light microscopy and enabled visualization of previously invisible molecular details …

Fluorescence nanoscopy in cell biology

SJ Sahl, SW Hell, S Jakobs - Nature reviews Molecular cell biology, 2017 - nature.com
Fluorescence nanoscopy uniquely combines minimally invasive optical access to the
internal nanoscale structure and dynamics of cells and tissues with molecular detection …

Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy

X Huang, J Fan, L Li, H Liu, R Wu, Y Wu, L Wei… - Nature …, 2018 - nature.com
To increase the temporal resolution and maximal imaging time of super-resolution (SR)
microscopy, we have developed a deconvolution algorithm for structured illumination …

Artificial neural networks enabled by nanophotonics

Q Zhang, H Yu, M Barbiero, B Wang… - Light: Science & …, 2019 - nature.com
The growing demands of brain science and artificial intelligence create an urgent need for
the development of artificial neural networks (ANNs) that can mimic the structural, functional …

Dendritic spines: Revisiting the physiological role

SB Chidambaram, AG Rathipriya, SR Bolla… - Progress in Neuro …, 2019 - Elsevier
Dendritic spines are small, thin, specialized protrusions from neuronal dendrites, primarily
localized in the excitatory synapses. Sophisticated imaging techniques revealed that …

[HTML][HTML] Super-resolution imaging of the extracellular space in living brain tissue

J Tønnesen, VVGK Inavalli, UV Nägerl - Cell, 2018 - cell.com
The extracellular space (ECS) of the brain has an extremely complex spatial organization,
which has defied conventional light microscopy. Consequently, despite a marked interest in …

The 2015 super-resolution microscopy roadmap

SW Hell, SJ Sahl, M Bates, X Zhuang… - Journal of Physics D …, 2015 - iopscience.iop.org
Far-field optical microscopy using focused light is an important tool in a number of scientific
disciplines including chemical,(bio) physical and biomedical research, particularly with …

Stimulated emission depletion microscopy

H Blom, J Widengren - Chemical reviews, 2017 - ACS Publications
Despite its short history, diffraction-unlimited fluorescence microscopy techniques have
already made a substantial imprint in the biological sciences. In this review, we describe …