Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …

Background In patients with ST-segment elevation myocardial infarction (STEMI) with
multivessel coronary artery disease, the time at which complete revascularization of …

Background The proprotein convertase subtilisin kexin type-9 inhibitor evolocumab
produced coronary atheroma regression in statin-treated patients. Objectives The purpose of …

Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed,
inflammatory mediators likely link many traditional and emerging risk factors with …

Background: Early detection of coronary atherosclerosis using coronary computed
tomography angiography (CCTA), in addition to coronary artery calcification (CAC) scoring …

Background Near-infrared spectroscopy (NIRS) and intravascular ultrasound are promising
imaging modalities to identify non-obstructive plaques likely to cause coronary-related …

OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Importance Coronary plaques that are prone to rupture and cause adverse cardiac events
are characterized by large plaque burden, large lipid content, and thin fibrous caps. Statins …

Background: Myocardial infarction with nonobstructive coronary arteries (MINOCA) occurs in
6% to 15% of myocardial infarctions (MIs) and disproportionately affects women. Scientific …