The Interplay between Ferroptosis and Neuroinflammation in Central Neurological Disorders

Y Xu, B Jia, J Li, Q Li, C Luo - Antioxidants, 2024 - mdpi.com
Central neurological disorders are significant contributors to morbidity, mortality, and long-
term disability globally in modern society. These encompass neurodegenerative diseases …

[HTML][HTML] Review of the Structural Characteristics and Biological Activities of Tricholoma Secondary Metabolites (2018–2023)

M Zhao, S Yuan, Z Li, C Liu, R Zhang - Molecules, 2024 - mdpi.com
Tricholoma are significant medicinal and edible mushrooms within Basidiomycota. Known
for their various medicinal properties such as anti-tumor, immune regulation, and antioxidant …

Targeting Nrf2/HO-1 and NF-κB/TNF-α signaling pathways with empagliflozin protects against atrial fibrillation-induced acute kidney injury in rats

H Badreldin, A El-Karef, T Ibrahim, M Elshal - Toxicology, 2024 - Elsevier
A bidirectional relationship exists between atrial fibrillation (AF) and kidney function.
Uncontrolled AF may lead to kidney injury, whereas renal dysfunction may contribute to AF …

[HTML][HTML] Bufalin alleviates inflammatory response and oxidative stress in experimental severe acute pancreatitis through activating Keap1-Nrf2/HO-1 and inhibiting NF …

X Niu, W Sun, X Tang, J Chen, H Zheng, G Yang… - International …, 2024 - Elsevier
Severe acute pancreatitis (SAP) is a prevalent acute inflammatory disease that is clinically
manifested by systemic inflammation dysregulation, resulting in a significantly elevated …

Tomatidine Alleviates Intervertebral Disc Degeneration by Activating the Nrf2/HO-1/GPX4 Signaling Pathway

Z Li, P Cheng, H Xi, T Jiang, X Zheng… - Drug Design …, 2024 - Taylor & Francis
Purpose Intervertebral disc degeneration (IDD) is a leading cause of low back pain, and
developing new molecular drugs and targets for IDD is a new direction for future treatment …

Taraxasterol extracted from Ixeridium gramineum (Fisch.) Tzvel. attenuated D-GalN/LPS-Induced Fulminant Hepatitis by modulating the JAK/STAT and TNF signalling …

Y Yin, R Lv, X Ling, H Cao, H Liu, J Wu, Y Gao… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Taraxasterol (TAR), a compound highly abundant and
easily obtainable from Tibetan medicine Ixeridium gramineum (Fisch.) Tzvel., exhibits a …