Systematic evolution of ligands by exponential enrichment (SELEX) has been used to
discover thousands of aptamers since its development in 1990. Aptamers are short single …

Fluorescence facilitates the detection, visualization, and tracking of molecules with high
sensitivity and specificity. A functional DNA molecule that generates a robust fluorescent …

Colorimetric assays in which the color of a solution changes in the presence of an input
provide a simple and inexpensive way to monitor experimental readouts. In this study we …

For many decades it was thought that information storage and information transfer were the
main functions of nucleic acids. However, artificial evolution experiments have shown that …

Artificial evolution experiments typically use libraries of∼ 1015 sequences and require
multiple rounds of selection to identify rare variants with a desired activity. Based on the …

Supernova is a chemiluminescent deoxyribozyme recently discovered in our group. It
transfers the phosphate group from the 1, 2‐dioxetane substrate CDP‐Star to its 5 …

Melamine is an illegal additive in milk products. Mel‐34 is an aptamer specific for melamine.
In this paper, we studied the base‐pair function in the stem regions of Mel‐34 using label …

The recent SARS-CoV-2 pandemic showed how humanity can be threatened by organisms
as simple as viruses. This crisis emphasized the need for timely and reliable diagnostics, as …