High-voltage electrical pulses in oncology: irreversible electroporation, electrochemotherapy, gene electrotransfer, electrofusion, and electroimmunotherapy

B Geboers, HJ Scheffer, PM Graybill, AH Ruarus… - Radiology, 2020 - pubs.rsna.org
This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …

Primer on pulsed electrical field ablation: understanding the benefits and limitations

A Verma, SJ Asivatham, T Deneke… - Circulation …, 2021 - Am Heart Assoc
Pulsed electrical field (PEF) energy is a promising technique for catheter ablation of cardiac
arrhythmias. In this article, the key aspects that need to be considered for safe and effective …

Electroporation-based technologies for medicine: principles, applications, and challenges

ML Yarmush, A Golberg, G Serša… - Annual review of …, 2014 - annualreviews.org
When high-amplitude, short-duration pulsed electric fields are applied to cells and tissues,
the permeability of the cell membranes and tissue is increased. This increase in permeability …

[HTML][HTML] Cytoreduction for colorectal metastases: liver, lung, peritoneum, lymph nodes, bone, brain. When does it palliate, prolong survival, and potentially cure?

CL Stewart, S Warner, K Ito, M Raoof… - Current problems in …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer commonly metastasizes. The liver is the most frequent site of metastases
and dominates the length of survival for this disease. As surgical and systemic therapies …

Irreversible electroporation for nonthermal tumor ablation in the clinical setting: a systematic review of safety and efficacy

HJ Scheffer, K Nielsen, MC de Jong… - Journal of Vascular and …, 2014 - Elsevier
Purpose To provide an overview of current clinical results of irreversible electroporation
(IRE), a novel, nonthermal tumor ablation technique that uses electric pulses to induce cell …

A review of basic to clinical studies of irreversible electroporation therapy

C Jiang, RV Davalos, JC Bischof - IEEE Transactions on …, 2014 - ieeexplore.ieee.org
The use of irreversible electroporation (IRE) for cancer treatment has increased sharply over
the past decade. As a nonthermal therapy, IRE offers several potential benefits over other …

Irreversible electroporation: background, theory, and review of recent developments in clinical oncology

KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …

Tumor ablation: common modalities and general practices

EM Knavel, CL Brace - Techniques in vascular and interventional radiology, 2013 - Elsevier
Tumor ablation is a minimally invasive technique that is commonly used in the treatment of
tumors of the liver, kidney, bone, and lung. During tumor ablation, thermal energy is used to …

Safety and early efficacy of irreversible electroporation for hepatic tumors in proximity to vital structures

R Cannon, S Ellis, D Hayes… - Journal of surgical …, 2013 - Wiley Online Library
Introduction Irreversible electroporation (IRE) has shown promise for ablation of lesions in
proximity to vital structures in the preclinical setting. This study aims to evaluate the safety …

High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction

CB Arena, MB Sano, JH Rossmeisl, JL Caldwell… - Biomedical engineering …, 2011 - Springer
Background Therapeutic irreversible electroporation (IRE) is an emerging technology for the
non-thermal ablation of tumors. The technique involves delivering a series of unipolar …