Mitochondrial antiviral signaling protein: a potential therapeutic target in renal disease

M Wu, Z Pei, G Long, H Chen, Z Jia, W Xia - Frontiers in Immunology, 2023 - frontiersin.org
Mitochondrial antiviral signaling protein (MAVS) is a key innate immune adaptor on the outer
mitochondrial membrane that acts as a switch in the immune signal transduction response to …

The roles of hyaluronan in kidney development, physiology and disease

TJ Rabelink, G Wang, J van der Vlag… - Nature Reviews …, 2024 - nature.com
The hyaluronan (HA) matrix in the tissue microenvironment is crucial for maintaining
homeostasis by regulating inflammatory signalling, endothelial–mesenchymal transition and …

Role of epigenetically regulated inflammation in renal diseases

J Jin, Y Yang, Q Gong, J Wang, W Ni, J Wen… - Seminars in Cell & …, 2024 - Elsevier
In recent decades, renal disease research has witnessed remarkable advances.
Experimental evidence in this field has highlighted the role of inflammation in kidney …

RG108 attenuates acute kidney injury by inhibiting P38 MAPK/FOS and JNK/JUN pathways

F Kong, H Liu, T Xu, S Li, W Li, H Lu, N Ma… - International …, 2024 - Elsevier
Acute kidney injury (AKI) is an important clinical syndrome characterised by a sudden
decline in renal function, often accompanied by renal inflammation and tubular epithelial cell …

The bach1/G9a/Slc7a11 axis epigenetically promotes renal fibrosis by mediated ferroptosis

X Yao, S Yang, L Chen, F Lin, Y Ruan, T Rao… - International …, 2024 - Elsevier
A high percentage of individuals with renal fibrosis are susceptible to developing chronic
kidney disease (CKD), and conventional therapy fails to halt the progression of renal fibrosis …

A novel role of DOT1L in kidney diseases

W Wei, Y Zhao, Y Chai, S Shou, H Jin - Molecular Biology Reports, 2023 - Springer
Background We systematically summarized the structure and biological function of DOT1L in
detail, and further discussed the role of DOT1L in kidney diseases through different …