Recent progress in continuous crystallization of pharmaceutical products: precise preparation and control
Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …
great diversity of crystalline pharmaceutical products. In recent years, continuous …
Consideration of the activity distribution using the population balance theory for designing a dual fluidized bed reactor-regenerator system. Application to the MTO …
The application of the population balance (PB) theory combined with a developed parallel
compartment (PC) model is proposed for a rigorous consideration of the activity distribution …
compartment (PC) model is proposed for a rigorous consideration of the activity distribution …
[HTML][HTML] Prediction of in vitro drug dissolution into fed-state biorelevant media: contributions of solubility enhancement and relatively low colloid diffusivity
A model was previously derived to predict in vitro dissolution of drug into surfactant solution
and showed good predictability for pharmaceutical surfactants, where surfactant-mediated …
and showed good predictability for pharmaceutical surfactants, where surfactant-mediated …
Coupling of CFD and population balance modelling for a continuously seeded helical tubular crystallizer
A comprehensive model coupling the computational fluid dynamics with the population
balance equation (CFD− PBE) for a continuous seeded mixed suspension mixed product …
balance equation (CFD− PBE) for a continuous seeded mixed suspension mixed product …
[HTML][HTML] Trajectory-based breakup modelling for dense bubbly flows
A new model to predict the breakup of gaseous bubbles in a continuous liquid phase is
developed. In the model each bubble is modelled as a spring–damper system, namely a …
developed. In the model each bubble is modelled as a spring–damper system, namely a …
A population balance model for the flow-induced preparation of Pickering emulsions
G Frungieri, H Briesen - Chemical Engineering Research and Design, 2023 - Elsevier
In this work we studied the flow-induced preparation of oil-in-water Pickering emulsions by
means of a bivariate population balance model. We characterized oil droplets by their size …
means of a bivariate population balance model. We characterized oil droplets by their size …
[HTML][HTML] Modelling of the leaching process by the extended quadrature method of moments
An approach based on the extended quadrature method of moments (EQMOM) has been
developed to solve the population balance equation written for the evolution of shrinking …
developed to solve the population balance equation written for the evolution of shrinking …
Design of particle size distribution for custom dissolution profiles by solving the inverse problem
Dissolution testing is widely used to measure the rate of drug release and predict its in-vivo
behavior. The release rate can be controlled by adjusting the particle size distribution (PSD) …
behavior. The release rate can be controlled by adjusting the particle size distribution (PSD) …
[HTML][HTML] Modeling simultaneous particle shrinkage, dissolution and breakage using the modified moving grid technique
Simultaneous shrinkage, dissolution and breakage are important particle size reduction
phenomena that characterize processes like the reactive degradation of solid chemicals …
phenomena that characterize processes like the reactive degradation of solid chemicals …
Kinetic modeling of methanol-to-olefins process over SAPO-34 catalysts in a dual fluidized bed reactor–regenerator
B Hejazi, N Shabany - Chemical Engineering Research and Design, 2022 - Elsevier
Based on a lumped methanol-to-olefins (MTO) reaction kinetic model over SAPO-34 catalyst
particles, a one-dimensional two-phase model was developed for bubbling fluidized bed …
particles, a one-dimensional two-phase model was developed for bubbling fluidized bed …