An overview and future prospects of sialic acids
H Yang, L Lu, X Chen - Biotechnology Advances, 2021 - Elsevier
Sialic acids (Sias) are negatively charged functional monosaccharides present in a wide
variety of natural sources (plants, animals and microorganisms). Sias play an important role …
variety of natural sources (plants, animals and microorganisms). Sias play an important role …
How bacteria utilize sialic acid during interactions with the host: snip, snatch, dispatch, match and attach
N-glycolylneuraminic acid (Neu5Gc), and its precursor N-acetylneuraminic acid (Neu5Ac),
commonly referred to as sialic acids, are two of the most common glycans found in …
commonly referred to as sialic acids, are two of the most common glycans found in …
Sialic acid plays a pivotal role in licensing Citrobacter rodentium's transition from the intestinal lumen to a mucosal adherent niche
Q Liang, C Ma, SM Crowley… - Proceedings of the …, 2023 - National Acad Sciences
Enteric bacterial pathogens pose significant threats to human health; however, the
mechanisms by which they infect the mammalian gut in the face of daunting host defenses …
mechanisms by which they infect the mammalian gut in the face of daunting host defenses …
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site
Many pathogenic bacteria utilise sialic acids as an energy source or use them as an external
coating to evade immune detection. As such, bacteria that colonise sialylated environments …
coating to evade immune detection. As such, bacteria that colonise sialylated environments …
Selective nutrient transport in bacteria: multicomponent transporter systems reign supreme
Multicomponent transporters are used by bacteria to transport a wide range of nutrients.
These systems use a substrate-binding protein to bind the nutrient with high affinity and then …
These systems use a substrate-binding protein to bind the nutrient with high affinity and then …
Sialic acid diversity in the human gut: molecular impacts and tools for future discovery
Sialic acids are a family of structurally related sugars that are prevalent in mucosal surfaces,
including the human intestine. In the gut, sialic acids have diverse biological roles at the …
including the human intestine. In the gut, sialic acids have diverse biological roles at the …
Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter
In bacteria and archaea, tripartite ATP-independent periplasmic (TRAP) transporters uptake
essential nutrients. TRAP transporters receive their substrates via a secreted soluble …
essential nutrients. TRAP transporters receive their substrates via a secreted soluble …
TRAPs: the 'elevator-with-an-operator'mechanism
Tripartite ATP-independent periplasmic (TRAP) transporters are nutrient-uptake systems
found in bacteria and archaea. These evolutionary divergent transporter systems couple a …
found in bacteria and archaea. These evolutionary divergent transporter systems couple a …
Enzymatic synthesis of sialic acids in microfluidics to overcome cross-inhibitions and substrate supply limitations
Multienzymatic cascade reactions are a powerful strategy for straightforward and highly
specific synthesis of complex materials, such as active substances in drugs. Cross …
specific synthesis of complex materials, such as active substances in drugs. Cross …
[HTML][HTML] On the function of TRAP substrate-binding proteins: conformational variation of the sialic acid binding protein SiaP
Tripartite ATP-independent periplasmic (TRAP) transporters are analogous to ABC
transporters in that they use a substrate-binding protein to scavenge metabolites (eg, N …
transporters in that they use a substrate-binding protein to scavenge metabolites (eg, N …