Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are effective antiobesity
drugs. However, the precise central mechanisms of GLP-1RAs remain elusive. We …

To understand the neural mechanisms of behavior, it is necessary to both monitor and
perturb the activity of ensembles of neurons with high specificity. While neural ensemble …

Highlights•Overview of genetically encoded calcium indicators (GECIs) based on fluorescent
and bioluminescent outputs.•Recent advances in calcium imaging with chemigenetic and …

Proteases function as pivotal molecular switches, initiating numerous biological events.
Notably, potyviral protease, derived from plant viruses, has emerged as a trusted proteolytic …

Isoflurane is one of the most widely used anesthetic agents in rodent imaging studies.
However, the impact of isoflurane on brain metabolism has not been fully characterized to …

Accumulating evidence has shown that various brain functions are associated with
experience-activated neuronal ensembles. However, whether such neuronal ensembles are …

The sensory neocortex has been suggested to be a substrate for long-term memory storage,
yet which exact single cells could be specific candidates underlying such long-term memory …

Behavior can be remarkably consistent, even over extended time periods, yet whether this is
reflected in stable or 'drifting'neuronal responses to task features remains controversial …

Social animals, including rodents, primates, and humans, partake in competition for finite
resources, thereby establishing social hierarchies wherein an individual's social standing …

The human brain represents one of the most complex biological systems, containing billions
of neurons interconnected through trillions of synapses. Inherent to the brain is a …