Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention

YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …

Role of oxidative damage in alzheimer's disease and neurodegeneration: From pathogenic mechanisms to biomarker discovery

FR Buccellato, M D'Anca, C Fenoglio, E Scarpini… - Antioxidants, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

Moving forward with isoprostanes, neuroprostanes and phytoprostanes: where are we now?

OS Ahmed, JM Galano, T Pavlickova… - Essays in …, 2020 - portlandpress.com
Polyunsaturated fatty acids (PUFAs) are essential components in eukaryotic cell membrane.
They take part in the regulation of cell signalling pathways and act as precursors in …

Advanced overview of biomarkers and techniques for early diagnosis of alzheimer's disease

S Rani, SB Dhar, A Khajuria, D Gupta… - Cellular and Molecular …, 2023 - Springer
The development of early non-invasive diagnosis methods and identification of novel
biomarkers are necessary for managing Alzheimer's disease (AD) and facilitating effective …

[HTML][HTML] Urinary biomarkers for neurodegenerative diseases

W Seol, H Kim, I Son - Experimental neurobiology, 2020 - ncbi.nlm.nih.gov
Global incidence of neurodegenerative diseases (NDDs) such as Alzheimer's disease (AD)
and Parkinson's disease (PD) is rapidly increasing, but the diagnosis of these diseases at …

Neuroprotective effects of DHA-derived peroxidation product 4 (RS)-4-F4t-neuroprostane on microglia

X Geng, JM Galano, C Oger, GY Sun, T Durand… - Free Radical Biology …, 2022 - Elsevier
The abundance of docosahexaenoic acid (DHA) in brain membrane phospholipids has
stimulated studies to explore its role in neurological functions. Upon released from …

The role of oxylipins and their validation as biomarkers in the clinical context

SM Camunas-Alberca, M Moran-Garrido, J Sáiz… - TrAC Trends in …, 2023 - Elsevier
Oxylipins are bioactive lipid mediators that participate in a wide range of processes, from
blood flow to inflammation. In recent years, their exhaustive characterization as potential …

Somatic mutations and Alzheimer's disease

J Downey, JCK Lam, VOK Li… - Journal of Alzheimer's …, 2022 - content.iospress.com
Alzheimer's disease (AD) represents a global health challenge, with an estimated 55 million
people suffering from the non-curable disease across the world. While amyloid-plaques and …

A transcriptome-wide association study identifies novel blood-based gene biomarker candidates for Alzheimer's disease risk

Y Sun, D Zhou, MR Rahman, J Zhu… - Human molecular …, 2022 - academic.oup.com
Alzheimer's disease (ad) adversely affects the health, quality of life and independence of
patients. There is a critical need to identify novel blood gene biomarkers for ad risk …

Associations of urinary 8‐iso‐prostaglandin F levels with all‐cause dementia, Alzheimer's disease, and vascular dementia incidence: results from a prospective …

K Trares, X Gào, L Perna, D Rujescu… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction Prospective studies on a potential association of 8‐iso‐prostaglandin F2α (8‐
iso‐PGF2α) levels, a biomarker of lipid peroxidation, with dementia are limited. Methods …