The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …

Lysophosphatidylcholine (LPC) is the main component of oxidatively damaged low-density
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …

Wide-scale profiling technologies including metabolomics broaden the possibility of novel
discoveries related to the pathogenesis of type 2 diabetes (T2D). By applying non-targeted …

Aim Scutellariae Radix (SR) and Coptidis Rhizoma (CR) have often been combined to cure
type 2 diabetes mellitus (T2DM) in the clinical practice for over thousands of years, but their …

Aims/hypothesis Metabolic effects of exercise may partly depend on the time-of-day when
exercise is performed. We tested the hypothesis that exercise timing affects the adaptations …

Metabolomic screening of fasting plasma from nondiabetic subjects identified α-
hydroxybutyrate (α-HB) and linoleoyl-glycerophosphocholine (L-GPC) as joint markers of …

Background Obesity and type 2 diabetes (T2DM) are associated with increased circulating
free fatty acids and triacylglycerols. However, very little is known about specific molecular …

Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases
(NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β …

Polycystic ovary syndrome (PCOS) represents one of the leading causes of anovulatory
infertility and affects 5% to 20% of women worldwide. Until today, both the subsequent …

Gestational Diabetes (GDM) is causing severe short-and long-term complications for mother,
fetus or neonate. As yet, the metabolic alterations that are specific for the development of …