Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

As the most dangerous tumors, brain tumors are usually treated with surgical removal,
radiation therapy, and chemotherapy. However, due to the aggressive growth of gliomas …

Various obstacles impede the chemotherapy efficiency of glioma in clinic, such as blood
brain barrier (BBB) and blood brain tumor barrier (BBTB). Ligand-mediated polymeric …

Traditional anti-cancer treatments are inefficient against glioblastoma, which remains one of
the deadliest and most aggressive cancers. Nano-drugs could help to improve this situation …

Autophagy modulation is considered to be a promising programmed cell death mechanism
to prevent and cure a great number of disorders and diseases. The crucial step in designing …

Cancer stem cells (CSCs) drive tumor initiation, progression, and therapeutic resistance due
to their self-renewal and differentiation capabilities. Despite encouraging progress in cancer …

Glioblastoma (GBM), classified as a grade IV glioma, is a rapidly growing, aggressive, and
most commonly occurring tumor of the central nervous system. Despite the therapeutic …

Synergistic therapies, such as chemo-photodynamic therapy, have been growing fast
because of their efficacy against cancers. Although metal–organic frameworks have been …

Nanotechnology-enabled ferroptosis therapy is an emerging paradigm for tumor treatment,
but amplifying ferroptotic damage in tumor cells in a safe and selective manner is still …

Autophagy is an evolutionarily conserved self-cannibalization process commonly found in
all eukaryotic cells. Through autophagy, long-lived or damaged organelles, superfluous …