Nutrigenetics, epigenetics and gestational diabetes: consequences in mother and child

M Franzago, F Fraticelli, L Stuppia, E Vitacolonna - Epigenetics, 2019 - Taylor & Francis
ABSTRACT Gestational Diabetes Mellitus (GDM) is the most common metabolic condition
during pregnancy and may result in short-and long-term complications for both mother and …

Genes and diet in the prevention of chronic diseases in future generations

M Franzago, D Santurbano, E Vitacolonna… - International journal of …, 2020 - mdpi.com
Nutrition is a modifiable key factor that is able to interact with both the genome and
epigenome to influence human health and fertility. In particular, specific genetic variants can …

Personalized nutrition in the management of female infertility: new insights on chronic low-grade inflammation

G Fabozzi, G Verdone, M Allori, D Cimadomo… - Nutrients, 2022 - mdpi.com
Increasing evidence on the significance of nutrition in reproduction is emerging from both
animal and human studies, suggesting a mutual association between nutrition and female …

Association of common genetic risk variants with gestational diabetes mellitus and their role in GDM prediction

PV Popova, AA Klyushina, LB Vasilyeva… - Frontiers in …, 2021 - frontiersin.org
Objective We aimed to explore the associations between common genetic risk variants with
gestational diabetes mellitus (GDM) risk in Russian women and to assess their utility in the …

The role of genetics and epigenetics in the pathogenesis of gestational diabetes mellitus

J Rosik, B Szostak, F Machaj… - Annals of human …, 2020 - Wiley Online Library
Diabetes mellitus (DM) is a heterogeneous group of disorders whose common trait is
chronic hyperglycemia. Gestational diabetes mellitus (GDM) is one of the subtypes of DM …

Molecular biomarkers for gestational diabetes mellitus and postpartum diabetes

W Lu, C Hu - Chinese Medical Journal, 2022 - mednexus.org
Gestational diabetes mellitus (GDM) is a growing public health problem worldwide that
threatens both maternal and fetal health. Identifying individuals at high risk for GDM and …

Type 2 diabetes linked FTO gene variant rs8050136 is significantly associated with gravidity in gestational diabetes in a sample of Bangladeshi women: Meta …

USM Amin, TA Rahman, M Hasan, T Tofail… - Plos one, 2023 - journals.plos.org
Objective Gestational diabetes mellitus (GDM) is a growing public health concern that has
not been extensively studied. Numerous studies have indicated that a variant (rs8050136) of …

The broad pathogenetic role of TCF7L2 in human diseases beyond type 2 diabetes

L del Bosque‐Plata… - Journal of Cellular …, 2022 - Wiley Online Library
The TCF7L2 protein is a key transcriptional effector of the Wnt/β‐catenin signaling pathway,
regulating gene expression. It was initially identified in cancer research and embryologic …

Association of type 2 diabetes susceptible genes GCKR, SLC30A8, and FTO polymorphisms with gestational diabetes mellitus risk: a meta-analysis

Z Lin, Y Wang, B Zhang, Z Jin - Endocrine, 2018 - Springer
Purpose Current studies have detected the correlation of polymorphisms in type 2 diabetes
susceptible genes GCKR, SLC30A8 and FTO with gestational diabetes mellitus (GDM) risk …

MTNR1B genetic polymorphisms as risk factors for gestational diabetes mellitus: a case-control study in a single tertiary care center

KK Alharbi, AM Al-Sulaiman… - Annals of Saudi …, 2019 - annsaudimed.net
ABSTRACT BACKGROUND: Gestational diabetes mellitus (GDM) is a metabolic disease in
pregnancy that causes carbohydrate intolerance and hyper-glycemia. Genome-wide …