Some of the factors involved in male infertility: a prospective review

E Babakhanzadeh, M Nazari… - … journal of general …, 2020 - Taylor & Francis
Infertility is defined as the inability of couples to have a baby after one year of regular
unprotected intercourse, affecting 10 to 15% of couples. According to the latest WHO …

Obesity and late-onset hypogonadism

G Corona, L Vignozzi, A Sforza, E Mannucci… - Molecular and cellular …, 2015 - Elsevier
Obesity and male hypogonadism (HG) are often associated, as demonstrated in all cross-
sectional studies. Prospective studies have indicated that i) having HG at baseline increases …

Critical evaluation of different available guidelines for late‐onset hypogonadism

VA Giagulli, M Castellana, G Lisco, V Triggiani - Andrology, 2020 - Wiley Online Library
Background Late‐onset hypogonadism (LOH) is a syndrome characterized by clinical and
biochemical evidence of low testosterone levels with advancing age. In recent years, several …

Effects of high-fat diet-induced obesity and diabetes on Kiss1 and GPR54 expression in the hypothalamic–pituitary–gonadal (HPG) axis and peripheral organs (fat …

M Dudek, PA Kołodziejski, E Pruszyńska-Oszmałek… - Neuropeptides, 2016 - Elsevier
Recent data indicates that kisspeptin, encoded by the KISS1 gene, could play a role in
transducing metabolic information into the hypothalamic–pituitary–gonadal (HPG) axis, the …

Role of sex hormones in diabetic nephropathy

J Liu, Z Liu, W Sun, L Luo, X An, D Yu… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is the most common microvascular complication in diabetes and
one of the leading causes of end-stage renal disease. The standard treatments for patients …

Injectable testosterone undecanoate for the treatment of hypogonadism

G Corona, E Maseroli, M Maggi - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Injectable testosterone undecanoate (TU) is a long-acting testosterone (T)
formulation available for the treatment of male hypogonadism (HG) since 2003. Areas …

Hypogonadism as a possible link between metabolic diseases and erectile dysfunction in aging men

G Corona, S Bianchini, A Sforza, L Vignozzi, M Maggi - Hormones, 2015 - Springer
There is evidence demonstrating that sexual complaints represent the most specific
symptoms associated with late onset hypogonadism, while central obesity is the most …

Weight loss more than glycemic control may improve testosterone in obese type 2 diabetes mellitus men with hypogonadism

VA Giagulli, M Castellana, MD Carbone, C Pelusi… - …, 2020 - Wiley Online Library
Background Functional hypogonadism is a common disorder among patients with obesity
and type 2 diabetes mellitus and could be managed by first treating the underlying causes …

Late‐onset hypogonadism and lifestyle‐related metabolic disorders

PC Braga, SC Pereira, JC Ribeiro, M Sousa… - …, 2020 - Wiley Online Library
Background Late‐onset hypogonadism (LOH) is a condition defined by low levels of
testosterone (T), occurring in advanced age. LOH is promoted by senescence, which, in turn …

Risk factors for hypogonadism in male patients with type 2 diabetes

R Zheng, L Cao, W Cao, X Chu, Y Hu… - Journal of diabetes …, 2016 - Wiley Online Library
Background. Male hypogonadism is an endocrine disease characterized by low levels of
serum testosterone and is closely related to the development of diabetes. The purpose of the …