The role of peroxisome proliferator-activated receptors (PPAR) in immune responses
Peroxisome proliferator-activated receptors (PPARs) are fatty acid-activated transcription
factors of nuclear hormone receptor superfamily that regulate energy metabolism. Currently …
factors of nuclear hormone receptor superfamily that regulate energy metabolism. Currently …
Rhabdomyosarcoma: current therapy, challenges, and future approaches to treatment strategies
Simple Summary Rhabdomyosarcoma (RMS) is a rare pediatric sarcoma affecting skeletal
muscle in children and young adults. It is responsible for 3% of all childhood malignant …
muscle in children and young adults. It is responsible for 3% of all childhood malignant …
Detection of the mitochondrial membrane potential by the cationic dye JC-1 in L1210 cells with massive overexpression of the plasma membrane ABCB1 drug …
K Elefantova, B Lakatos, J Kubickova, Z Sulova… - International journal of …, 2018 - mdpi.com
JC-1, a cationic fluorescent dye when added to living cells, is known to be localized
exclusively in mitochondria, particularly in good physiological conditions characterized by …
exclusively in mitochondria, particularly in good physiological conditions characterized by …
Interaction between phytotherapy and oral anticancer agents: prospective study and literature review
AL Clairet, M Boiteux-Jurain, E Curtit, M Jeannin… - Medical Oncology, 2019 - Springer
Cancer is becoming more prevalent in elderly patient. Due to polypharmacy, older adults
with cancer are predisposed to drug-drug interactions. There is also an increasing interest in …
with cancer are predisposed to drug-drug interactions. There is also an increasing interest in …
NRF 2/ABCB 1‐mediated efflux and PARP 1‐mediated dampening of DNA damage contribute to doxorubicin resistance in chronic hypoxic HepG2 cells
X Xia, Q Wang, T Ye, Y Liu, D Liu… - Fundamental & …, 2020 - Wiley Online Library
Transarterial chemoembolization (TACE)‐induced hypoxia can trigger residual liver cancer
cells to present a more aggressive phenotype associated with chemoresistance, but the …
cells to present a more aggressive phenotype associated with chemoresistance, but the …
Testing of the survivin suppressant YM155 in a large panel of drug-resistant neuroblastoma cell lines
M Michaelis, Y Voges, F Rothweiler, F Weipert… - Cancers, 2020 - mdpi.com
The survivin suppressant YM155 is a drug candidate for neuroblastoma. Here, we tested
YM155 in 101 neuroblastoma cell lines (19 parental cell lines, 82 drug-adapted sublines) …
YM155 in 101 neuroblastoma cell lines (19 parental cell lines, 82 drug-adapted sublines) …