[HTML][HTML] Lipidomes in health and disease: Analytical strategies and considerations
F Wei, S Lamichhane, M Orešič… - TrAC Trends in Analytical …, 2019 - Elsevier
Lipidomics is a rapidly-growing field which focuses on global characterization of lipids at
molecular and systems levels. As small changes in the concentrations of lipids may have …
molecular and systems levels. As small changes in the concentrations of lipids may have …
Serum metabolome associated with severity of acute traumatic brain injury
Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain
injury (TBI). Associations between this and systemic metabolism and their potential …
injury (TBI). Associations between this and systemic metabolism and their potential …
Analytical challenges in human exposome analysis with focus on environmental analysis combined with metabolomics
T Hyötyläinen - Journal of Separation Science, 2021 - Wiley Online Library
Environmental factors, such as chemical exposures, are likely to play a crucial role in the
development of several human chronic diseases. However, how the specific exposures …
development of several human chronic diseases. However, how the specific exposures …
Metabolic alterations in immune cells associate with progression to type 1 diabetes
P Sen, AM Dickens, MA López-Bascón, T Lindeman… - Diabetologia, 2020 - Springer
Aims/hypothesis Previous metabolomics studies suggest that type 1 diabetes is preceded by
specific metabolic disturbances. The aim of this study was to investigate whether distinct …
specific metabolic disturbances. The aim of this study was to investigate whether distinct …
Prenatal exposure to poly-/per-fluoroalkyl substances is associated with alteration of lipid profiles in cord-blood
Introduction Poly-/per-fluoroalkyl substances (PFAS) are widespread environmental
pollutants that may induce metabolic perturbations in humans, including particularly …
pollutants that may induce metabolic perturbations in humans, including particularly …
[HTML][HTML] Early-life exposure to perfluorinated alkyl substances modulates lipid metabolism in progression to celiac disease
Celiac disease (CD) is a systemic immune-mediated disorder with increased frequency in
the developed countries over the last decades implicating the potential causal role of …
the developed countries over the last decades implicating the potential causal role of …
Per-and polyfluoroalkyl substance plasma concentrations and metabolomic markers of type 2 diabetes in the Diabetes Prevention Program trial
Background Per-and polyfluoroalkyl substances (PFAS) are widely used chemicals, some of
which have been linked to type 2 diabetes. We tested whether PFAS concentrations were …
which have been linked to type 2 diabetes. We tested whether PFAS concentrations were …
Cord serum metabolic signatures of future progression to immune-mediated diseases
Previous prospective studies suggest that progression to autoimmune diseases is preceded
by metabolic dysregulation, but it is not clear which metabolic changes are disease-specific …
by metabolic dysregulation, but it is not clear which metabolic changes are disease-specific …
Lipidomic analyses reveal modulation of lipid metabolism by the PFAS perfluoroundecanoic acid (PFUnDA) in non-obese diabetic mice
Exposure to Per-and polyfluoroalkyl substances (PFAS) has been linked to multiple
undesirable health outcomes across a full lifespan, both in animal models as well as in …
undesirable health outcomes across a full lifespan, both in animal models as well as in …
Potential transdiagnostic lipid mediators of inflammatory activity in individuals with Serious Mental illness
Mental disorders are heterogeneous and psychiatric comorbidities are common. Previous
studies have suggested a link between inflammation and mental disorders. This link can …
studies have suggested a link between inflammation and mental disorders. This link can …