Abstract Philadelphia (Ph) chromosome (9; 22)(q34; q11) comprises 90–95% of chronic
myeloid leukemia (CML), while 5–10% of CML have translocations involving three or more …

Interventions: The patients received continuously oral imatinib mesylate tablets (400 mg)
once a day. Outcomes: After treatment with imatinib for 3 months, the BCR/ABL IS was less …

Background The vast majority of chronic myeloid leukemia (CML) patients have a single
translocation t (9; 22)(q34; q11), BCR/ABL1 fusion genes, which is regarded as the hallmark …

Chromosomal translocations (CTs) are the most common type of structural chromosomal
abnormalities in humans. CTs have been reported in several studies in the Arab world, but …

Abstract 90% of Chronic Myeloid Leukemia (CML) patients having Philadelphia (Ph)
chromosome or t (9; 22)(q34; q11. 2), and the remaining 5–8% of CML patients demonstrate …

Chronic myeloid leukemia (CML) is classified as a hematological malignant rare disease by
National Organization for Rare Disease (NORD, USA) based on the estimated incidence of …

Objective To analyze the feasibility of detecting Ph 1 in leukemia patients in the Kinshasa
University Clinics in the Democratic Republic of Congo, at KU Leuven, Belgium. Methods …

Clinical presentation of chronic myeloid leukemia (CML) with classic translocation is similar
to those with variant translocations. However, the disease course, outcome and prognosis …

Aim: Chronic myeloid leukemia (CML) is characterized by a fusion of the BCR-ABL gene as
the result of a reciprocal translocation of chromosomes 9 and 22 forming the Philadelphia …

Cilj: Obilježje kronične mijeloične leukemije (KML) je hibridni BCR-ABL gen nastao kao
posljedica recipročne translokacije između kromosoma 9 i 22, čime se stvara Philadelphia …