Role of lung and gut microbiota on lung cancer pathogenesis

Y Zhao, Y Liu, S Li, Z Peng, X Liu, J Chen… - Journal of Cancer …, 2021 - Springer
Background Lung cancer is the leading cause of cancer-related deaths worldwide (Ferlay et
al., Int J Cancer 136: E359–386, 2015). In addition, lung cancer is associated with the …

Role of gut microbiome in cancer immunotherapy: from predictive biomarker to therapeutic target

M Zhang, J Liu, Q Xia - Experimental Hematology & Oncology, 2023 - Springer
Immunotherapy has emerged as an effective treatment for various types of cancers. Recent
studies have highlighted a significant correlation between the gut microbiome and patients' …

CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies

Y Hu, J Li, F Ni, Z Yang, X Gui, Z Bao, H Zhao… - Nature …, 2022 - nature.com
Immunotherapy utilizing chimeric antigen receptor T cell (CAR-T) therapy holds promise for
hematologic malignancies, however, response rates and associated immune-related …

Network analysis of gut microbiome and metabolome to discover microbiota-linked biomarkers in patients affected by non-small cell lung cancer

P Vernocchi, T Gili, F Conte, F Del Chierico… - International Journal of …, 2020 - mdpi.com
Several studies in recent times have linked gut microbiome (GM) diversity to the
pathogenesis of cancer and its role in disease progression through immune response …

Gut microbiota in lung cancer: where do we stand?

K Georgiou, B Marinov, AA Farooqi… - International journal of …, 2021 - mdpi.com
The gut microbiota (GM) is considered to constitute a powerful “organ” capable of
influencing the majority of the metabolic, nutritional, physiological, and immunological …

Beyond PD-L1 markers for lung cancer immunotherapy

K Wojas-Krawczyk, E Kalinka, A Grenda… - International journal of …, 2019 - mdpi.com
Immunotherapy using immune checkpoints inhibitors has become the standard treatment for
first and second line therapy in patients with non-small cell lung cancer (NSCLC). However …

Current status and development of anti-PD-1/PD-L1 immunotherapy for lung cancer

L Wang, Q Ma, R Yao, J Liu - International immunopharmacology, 2020 - Elsevier
Lung cancer is the leading cause of cancer deaths worldwide, mainly because it is usually in
the advanced stage at the time of diagnosis. Although great progress has been made in the …

Lung and gut microbiota as potential hidden driver of immunotherapy efficacy in lung cancer

C Carbone, G Piro, V Di Noia… - Mediators of …, 2019 - Wiley Online Library
Lung cancer is one of the deadliest and most common malignancies in the world,
representing one of the greatest challenges in cancer treatment. Immunotherapy is rapidly …

[HTML][HTML] Microbiome bacterial influencers of host immunity and response to immunotherapy

Y Yousefi, KJ Baines, SM Vareki - Cell Reports Medicine, 2024 - cell.com
The gut microbiota influences anti-tumor immunity and can induce or inhibit response to
immune checkpoint inhibitors (ICIs). Therefore, microbiome features are being studied as …

The role of the microbiome in cancer and therapy efficacy: focus on lung cancer

A Halley, A Leonetti, A Gregori, M Tiseo… - Anticancer …, 2020 - ar.iiarjournals.org
The microbiome is extremely important for human health; more recently its role in the context
of cancer became clear. Microbial effects range from enhancing cancer immunity and cancer …