IL-17 in the pathogenesis of disease: good intentions gone awry

S Majumder, MJ McGeachy - Annual review of immunology, 2021 - annualreviews.org
The IL-17 family is an evolutionarily old cytokine family consisting of six members (IL-17A
through IL-17F). IL-17 family cytokines signal through heterodimeric receptors that include …

Consequences of viral infection and cytokine production during pregnancy on brain development in offspring

D Elgueta, P Murgas, E Riquelme, G Yang… - Frontiers in …, 2022 - frontiersin.org
Infections during pregnancy can seriously damage fetal neurodevelopment by aberrantly
activating the maternal immune system, directly impacting fetal neural cells. Increasing …

Advances in the study of IL-17 in neurological diseases and mental disorders

Y Lu, P Zhang, F Xu, Y Zheng, H Zhao - Frontiers in Neurology, 2023 - frontiersin.org
Interleukin-17 (IL-17), a cytokine characteristically secreted by T helper 17 (Th17) cells, has
attracted increasing attention in recent years because of its importance in the pathogenesis …

[HTML][HTML] Placental dysfunction: the core mechanism for poor neurodevelopmental outcomes in the offspring of preeclampsia pregnancies

D Liu, Q Gao, Y Wang, T Xiong - Placenta, 2022 - Elsevier
Preeclampsia (PE) is a leading condition threatening pregnant women and their offspring.
The offspring of PE pregnancies have a high risk of poor neurodevelopmental outcomes and …

Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids

M Notaras, A Lodhi, E Barrio-Alonso, C Foord… - Molecular …, 2021 - nature.com
It is widely accepted that narcotic use during pregnancy and specific environmental factors
(eg, maternal immune activation and chronic stress) may increase risk of neuropsychiatric …

Neuronal cell adhesion molecules may mediate neuroinflammation in autism spectrum disorder

M Eve, J Gandawijaya, L Yang… - Frontiers in Psychiatry, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized
by restrictive and repetitive behaviors, alongside deficits in social interaction and …

Aberrant IL-17 levels in rodent models of autism Spectrum disorder: a systematic review

AJ Thawley, LP Veneziani… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder
characterised by stereotyped behaviours, specific interests, and impaired communication …

Adult mouse hippocampal transcriptome changes associated with long-term behavioral and metabolic effects of gestational air pollution toxicity

A Haghani, RG Johnson, NC Woodward… - Translational …, 2020 - nature.com
Gestational exposure to air pollution increases the risk of autism spectrum disorder and
cognitive impairments with unresolved molecular mechanisms. This study exposed …

Risk of attention deficit hyperactivity and autism spectrum disorders among the children of parents with autoimmune diseases: a nationwide birth cohort study

H Lee, JW Hsu, SJ Tsai, KL Huang, YM Bai… - European Child & …, 2023 - Springer
Studies have suggested that maternal autoimmune diseases are associated with an
increased risk of attention deficit hyperactivity disorder (ADHD) and autism spectrum …

The effects of maternal interleukin-17A on social behavior, cognitive function, and depression-like behavior in mice with altered kynurenine metabolites

Y Murakami, Y Imamura, Y Kasahara… - International …, 2021 - journals.sagepub.com
Viral infection and chronic maternal inflammation during pregnancy are correlated with a
higher prevalence of autism spectrum disorder (ASD). However, the pathoetiology of ASD is …