What animal models can tell us about long-term cognitive dysfunction following sepsis: a systematic review

FF Savi, A de Oliveira, GF de Medeiros… - Neuroscience & …, 2021 - Elsevier
Survivors of sepsis often develop long-term cognitive impairments. This review aimed at
exploring the results of the behavioral tools and tests which have been used to evaluate …

Long-term cognitive outcomes after sepsis: a translational systematic review

T Barichello, P Sayana, VV Giridharan… - Molecular …, 2019 - Springer
Sepsis is systemic inflammatory response syndrome with a life-threatening organ
dysfunction that is caused by an unbalanced host immune response in an attempt to …

Nicotine's effect on cognition, a friend or foe?

Q Wang, W Du, H Wang, P Geng, Y Sun… - Progress in Neuro …, 2023 - Elsevier
Tobacco smoking is a preventable cause of morbidity and mortality throughout the world.
Smoking comes in form of absorption of many compounds, among which nicotine is the …

Cortistatin‐14 Exerts Neuroprotective Effect Against Microglial Activation, Blood‐brain Barrier Disruption, and Cognitive Impairment in Sepsis‐associated …

Q Wen, Q Ding, J Wang, Y Yin, S Xu… - Journal of …, 2022 - Wiley Online Library
Sepsis‐associated encephalopathy (SAE) is a life‐threatening deterioration of mental status
in relation to long‐term and disabling cognitive dysfunction that is common in intensive care …

Rho-proteins and downstream pathways as potential targets in sepsis and septic shock: what have we learned from basic research

MLS Hahmeyer, JE da Silva-Santos - Cells, 2021 - mdpi.com
Sepsis and septic shock are associated with acute and sustained impairment in the function
of the cardiovascular system, kidneys, lungs, liver, and brain, among others. Despite the …

[HTML][HTML] What animal models can tell us about long-term psychiatric symptoms in sepsis survivors: a systematic review

F Dal-Pizzol, GF de Medeiros, M Michels, A Mazeraud… - …, 2021 - Elsevier
Lower sepsis mortality rates imply that more patients are discharged from the hospital, but
sepsis survivors often experience sequelae, such as functional disability, cognitive …

Effect of dietary supplements with ω-3 Fatty Acids, Ascorbic Acid, and Polyphenolic Antioxidant Flavonoid on gene expression, organ failure, and mortality in …

Y Prado, C Echeverría, CG Feijóo, CA Riedel… - Antioxidants, 2023 - mdpi.com
Sepsis syndrome develops through enhanced secretion of pro-inflammatory cytokines and
the generation of reactive oxygen species (ROS). Sepsis syndrome is characterized by …

Post-sepsis psychiatric disorder: Pathophysiology, prevention, and treatment

D Li, X Zhang, Y Lu, L Jing, H Hu, Y Song, S Wu… - Neurological …, 2024 - Springer
Post-sepsis psychiatric disorder, encompassing anxiety, depression, post-traumatic stress
disorder and delirium, is a highly prevalent complication secondary to sepsis, resulting in a …

Effects of caffeine on behavioural and cognitive deficits in rats

MS Assis, AC Soares, DN Sousa… - Basic & clinical …, 2018 - Wiley Online Library
There are many studies that have sought to find drug therapies to prevent harm arising from
sepsis. Such studies have represented a progress in the support to septic patients and also …

Effects of intravenous immunoglobulin therapy on behavior deficits and functions in sepsis model

PE Ozcan, E Senturk, G Orhun, S Gumru… - Annals of Intensive …, 2015 - Springer
Background We aim to demonstrate behavioral alterations in a sepsis model using
intravenous (IV) immunoglobulin G (IgG) and immunoglobulins enriched with IgA and IgM …