The recapitulation of complex microenvironments that regulate cell behavior during
development, disease, and wound healing is key to understanding fundamental biological …

Modeling the heterogeneity of the tumor microenvironment (TME) in vitro is essential to
investigating fundamental cancer biology and developing novel treatment strategies that …

Osteochondral tissue has a complex hierarchical structure spanning subchondral bone to
articular cartilage. Biomaterials approaches to mimic and repair these interfaces have had …

Nowadays, there are still many challenges to skin regeneration. As a new type of skin
substitute, hydrogel has emerging gradually with its excellent properties. However, it is still a …

During tissue development, stem and progenitor cells form functional tissue with high
cellular diversity and intricate micro‐and macro‐architecture. Current approaches have …

The tissue microenvironment contains a complex assortment of multiple cell types, matrices,
and vessel structures, which is difficult to reconstruct in vitro. Here, we demonstrate model …

An organoid, a self-organizing organ-like tissue developed from stem cells, can exhibit a
miniaturized three-dimensional (3D) structure and part of the physiological functions of the …

Engineered culture substrates have proven invaluable for investigating the role of cell and
extracellular matrix geometry in governing cell behavior. While the mechanisms relating …

Dormant, disseminated tumor cells (DTCs) can persist for decades in secondary tissues
before being reactivated to form tumors. The properties of the premetastatic niche can …

Dynamic cell‐culture materials that can change mechanical properties in response to
extrinsic stimuli are emerging as promising tools for cell and tissue engineering research …