Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …

Despite a long history, Wilson's disease, an autosomal recessive disease caused by
mutations in the ATP7B gene, remains a commonly misdiagnosed import disease. Mutations …

Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

Introduction Study of MRI changes may be useful in diagnosis, prognosis and better
understanding of the pathophysiology of Wilson's disease (WD). We aimed to describe and …

The purpose of the study was to describe the range of abnormalities seen on cranial MR
images of patients with Wilson's disease and correlate the findings with clinical severity …

Neurologic symptoms in Wilson disease (WD) appear at an older age compared to hepatic
symptoms and manifest in patients with misdiagnosed liver disease, in patients when the …

PURPOSE: To describe the spectrum of brain abnormalities in Wilson disease
(hepatolenticular degeneration) as depicted at magnetic resonance (MR) imaging and …

Background & Aims Risk factors for cardiovascular disease, such as obesity and
hypertension, have been associated with nonalcoholic fatty liver disease. Psychological …

BACKGROUND AND PURPOSE: Although brain MR imaging findings in adult Wilson
disease have been described in considerable detail, a paucity of information currently exists …

This report reviews clinical neuropsychiatric findings and opportunities for research in
Huntington's, Wilson's, and Fahr's diseases. Consistent, systematic methodology is lacking …