[HTML][HTML] Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment
P Graván, A Aguilera-Garrido, JA Marchal… - Advances in Colloid and …, 2023 - Elsevier
Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …
therapeutics as they improve the pharmacokinetic profile and distribution of …
Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines
Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …
absorption, low specificity, rapid degradation, and resistance development. The design and …
Topical formulations containing aptamer-functionalized nanocapsules loaded with 5-fluorouracil-An innovative concept for the skin cancer therapy
DM Rata, AN Cadinoiu, LI Atanase, M Popa… - Materials Science and …, 2021 - Elsevier
New topical gel formulations based on sodium alginate and hyaluronic acid containing
AS1411 aptamer-functionalized polymeric nanocapsules loaded with an antitumoral drug (5 …
AS1411 aptamer-functionalized polymeric nanocapsules loaded with an antitumoral drug (5 …
Synthesis of 5-fluorouracil cocrystals with novel organic acids as coformers and anticancer evaluation against HCT-116 colorectal cell lines
F Jubeen, A Liaqat, F Amjad, M Sultan… - Crystal Growth & …, 2020 - ACS Publications
5-Fluorouracil (5-FU) being a mainstream anticancer drug is under keen and detailed
investigation for prodrugs formulations in order to minimize the associated side effects …
investigation for prodrugs formulations in order to minimize the associated side effects …
[HTML][HTML] Formulations based on drug loaded aptamer-conjugated liposomes as a viable strategy for the topical treatment of basal cell carcinoma—in vitro tests
AN Cadinoiu, DM Rata, LI Atanase, CT Mihai… - Pharmaceutics, 2021 - mdpi.com
Topical liposomal drug formulations containing AS1411-aptamer conjugated liposomes
were designed to deliver in a sustained way the 5-fluorouracil to the tumor site but also to …
were designed to deliver in a sustained way the 5-fluorouracil to the tumor site but also to …
[HTML][HTML] Mesenchymal stem cell‑derived exosomes loaded with 5‑Fu against cholangiocarcinoma in vitro
M Chen, Y Li, N Ma, J Zang - Molecular Medicine …, 2022 - spandidos-publications.com
Cholangiocarcinoma (CCA) is an intractable malignant tumour with a high degree of
malignancy that is asymptomatic in the early stages. Exosomes have been shown in …
malignancy that is asymptomatic in the early stages. Exosomes have been shown in …
Body composition, relative dose intensity, and adverse events among patients with colon cancer
Background: Despite evidence that low muscle increases the risk of chemotoxicity, most
chemotherapies are dosed on body surface area without considering body composition …
chemotherapies are dosed on body surface area without considering body composition …
[HTML][HTML] Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules
L Pinton, S Magri, E Masetto, M Vettore… - Journal of …, 2020 - Springer
Background Myeloid derived suppressor cells (MDSCs) and tumor-associated macrophages
(TAMs) are two of the major players involved in the inhibition of anti-tumor immune response …
(TAMs) are two of the major players involved in the inhibition of anti-tumor immune response …
5-Fluorouracil drug delivery system based on bacterial nanocellulose for colorectal cancer treatment: Mathematical and in vitro evaluation
E Martínez, M Osorio, C Finkielstein, I Ortíz… - International Journal of …, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common worldwide. Its treatment includes
adjuvant chemotherapy with 5-fluorouracil (5FU) administered intravenously. 5FU is an …
adjuvant chemotherapy with 5-fluorouracil (5FU) administered intravenously. 5FU is an …
Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules
NA El-Sheridy, RM El-Moslemany, AA Ramadan… - Drug …, 2021 - Taylor & Francis
Abstract Itraconazole (ITC), a well-tolerated antifungal drug, exerts multiple anticancer
effects which justified its preclinical and clinical investigation as potential anti-cancer agent …
effects which justified its preclinical and clinical investigation as potential anti-cancer agent …