Release and persistence of extracellular DNA in the environment

KM Nielsen, PJ Johnsen, D Bensasson… - Environmental …, 2007 - ebr-journal.org
The introduction of genetically modified organisms (GMOs) has called for an improved
understanding of the fate of DNA in various environments, because extracellular DNA may …

Building-in biosafety for synthetic biology

O Wright, GB Stan, T Ellis - Microbiology, 2013 - microbiologyresearch.org
As the field of synthetic biology develops, real-world applications are moving from the
realms of ideas and laboratory-confined research towards implementation. A pressing …

Cellular biosensors with engineered genetic circuits

B Saltepe, ES Kehribar, SS Su Yirmibeşoğlu… - ACS …, 2018 - ACS Publications
An increasing interest in building novel biological devices with designed cellular
functionalities has triggered the search of innovative tools for biocomputation. Utilizing the …

In-situ monitoring of xenobiotics using genetically engineered whole-cell-based microbial biosensors: recent advances and outlook

SA Ali, D Mittal, G Kaur - World Journal of Microbiology and Biotechnology, 2021 - Springer
Industrialisation, directly or indirectly, exposes humans to various xenobiotics. The
increased magnitude of chemical pesticides and toxic heavy metals in the environment, as …

Detecting rare gene transfer events in bacterial populations

KM Nielsen, T Bøhn, JP Townsend - Frontiers in microbiology, 2014 - frontiersin.org
Horizontal gene transfer (HGT) enables bacteria to access, share, and recombine genetic
variation, resulting in genetic diversity that cannot be obtained through mutational processes …

Guidance on the environmental risk assessment of genetically modified animals

EFSA Panel on Genetically Modified Organisms … - EFSA …, 2013 - Wiley Online Library
This document provides guidance for the environmental risk assessment (ERA) of living
genetically modified (GM) animals, namely fish, insects and mammals and birds, to be …

Assessing the probability of detection of horizontal gene transfer events in bacterial populations

JP Townsend, T Bøhn, KM Nielsen - Frontiers in microbiology, 2012 - frontiersin.org
Experimental approaches to identify horizontal gene transfer (HGT) events of non-mobile
DNA in bacteria have typically relied on detection of the initial transformants or their …

An investigation of horizontal transfer of feed introduced DNA to the aerobic microbiota of the gastrointestinal tract of rats

L Nordgård, L Brusetti, N Raddadi, T Traavik… - BMC research …, 2012 - Springer
Background Horizontal gene transfer through natural transformation of members of the
microbiota of the lower gastrointestinal tract (GIT) of mammals has not yet been described …

Lack of detectable DNA uptake by bacterial gut isolates grown in vitro and by Acinetobacter baylyi colonizing rodents in vivo

L Nordgård, T Nguyen, T Midtvedt, Y Benno… - Environmental …, 2007 - cambridge.org
Biological risk assessment of food containing recombinant DNA has exposed knowledge
gaps related to the general fate of DNA in the gastrointestinal tract (GIT). Here, a series of …

Low prevalence of blaTEM genes in Arctic environments and agricultural soil and rhizosphere

L Brusetti, T Glad, S Borin, P Myren, A Rizzi… - Microbial Ecology in …, 2008 - Taylor & Francis
The prevalence of bla TEM genes conferring ampicillin resistance (Ampr) in different soils
was determined to clarify the environmental distribution of resistance determinants of major …