Applications of multi‐omics analysis in human diseases

C Chen, J Wang, D Pan, X Wang, Y Xu, J Yan… - MedComm, 2023 - Wiley Online Library
Multi‐omics usually refers to the crossover application of multiple high‐throughput screening
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …

A review of deep learning applications in human genomics using next-generation sequencing data

WS Alharbi, M Rashid - Human Genomics, 2022 - Springer
Genomics is advancing towards data-driven science. Through the advent of high-throughput
data generating technologies in human genomics, we are overwhelmed with the heap of …

Field guide to next‐generation DNA sequencers

TC Glenn - Molecular ecology resources, 2011 - Wiley Online Library
The diversity of available 2nd and 3rd generation DNA sequencing platforms is increasing
rapidly. Costs for these systems range from< 100000tomorethan 1 000 000, with instrument …

Next-generation sequencing—an overview of the history, tools, and “Omic” applications

JK Kulski - Next generation sequencing-advances, applications …, 2016 - books.google.com
Next-generation sequencing (NGS) technologies using DNA, RNA, or methylation
sequencing have impacted enormously on the life sciences. NGS is the choice for large …

dbNSFP: a lightweight database of human nonsynonymous SNPs and their functional predictions

X Liu, X Jian, E Boerwinkle - Human mutation, 2011 - Wiley Online Library
With the advance of sequencing technologies, whole exome sequencing has increasingly
been used to identify mutations that cause human diseases, especially rare Mendelian …

Emerging trends in genetic engineering of microalgae for commercial applications

SB Grama, Z Liu, J Li - Marine Drugs, 2022 - mdpi.com
Recently, microalgal biotechnology has received increasing interests in producing valuable,
sustainable and environmentally friendly bioproducts. The development of economically …

Historical perspective, development and applications of next-generation sequencing in plant virology

M Barba, H Czosnek, A Hadidi - Viruses, 2014 - mdpi.com
Next-generation high throughput sequencing technologies became available at the onset of
the 21st century. They provide a highly efficient, rapid, and low cost DNA sequencing …

Uncovering the complexity of transcriptomes with RNA‐Seq

V Costa, C Angelini, I De Feis… - BioMed Research …, 2010 - Wiley Online Library
In recent years, the introduction of massively parallel sequencing platforms for Next
Generation Sequencing (NGS) protocols, able to simultaneously sequence hundred …

Applications of next‐generation sequencing in plant biology

AN Egan, J Schlueter… - American journal of …, 2012 - Wiley Online Library
The last several years have seen revolutionary advances in DNA sequencing technologies
with the advent of next‐generation sequencing (NGS) techniques. NGS methods now allow …

Application of genomic tools in plant breeding

A M. Perez-de-Castro, S Vilanova, J Cañizares… - Current …, 2012 - benthamdirect.com
Plant breeding has been very successful in developing improved varieties using
conventional tools and methodologies. Nowadays, the availability of genomic tools and …