Photodynamic therapy with fullerenes

P Mroz, GP Tegos, H Gali, T Wharton, T Sarna… - Photochemical & …, 2007 - Springer
Fullerenes are a class of closed-cage nanomaterials made exclusively from carbon atoms. A
great deal of attention has been focused on developing medical uses of these unique …

Toxicity of pristine versus functionalized fullerenes: mechanisms of cell damage and the role of oxidative stress

A Trpkovic, B Todorovic-Markovic, V Trajkovic - Archives of toxicology, 2012 - Springer
The fullerene C 60, due to the physicochemical properties of its spherical cage-like molecule
build exclusively from carbon atoms, is able to both scavenge and generate reactive oxygen …

Self-assembling nanostructures of water-soluble fullerene [60]–chlorin e6 dyads: Synthesis, photophysical properties, and photodynamic activity

AY Rybkin, AY Belik, NS Goryachev, PA Mikhaylov… - Dyes and …, 2020 - Elsevier
The synthesis of water-soluble dyads PFD-Chl (1), PFD-Chl (Zn) and PFD-Chl (2) based on
a polyanionic fullerene [60] derivative PFD covalently linked to chlorin e 6 was described …

Assessing Photosensitized Membrane Damage: Available Tools and Comprehensive Mechanisms

LG Rezende, TT Tasso, PHS Candido… - Photochemistry and …, 2022 - Wiley Online Library
Lipids are important targets of the photosensitized oxidation reactions, forming important
signaling molecules, disorganizing and permeabilizing membranes, and consequently …

Hemocompatibility of carbon nanostructures

M Fedel - C, 2020 - mdpi.com
Carbon nanostructures (CNs), such as carbon nanotubes, fullerenes, carbon dots,
nanodiamonds as well as graphene and its derivatives present a tremendous potential for …

Hybrid photoactive fullerene derivative–ruboxyl nanostructures for photodynamic therapy

AI Kotelnikov, AY Rybkin, EA Khakina… - Organic & …, 2013 - pubs.rsc.org
Here we report the investigation of photophysical properties and photodynamic action of two
novel water soluble hybrid molecular structures based on [60] fullerene dyads bearing …

Twenty years of promises: fullerene in medicinal chemistry

T Da Ros - Medicinal Chemistry and Pharmacological Potential of …, 2008 - Springer
Many biological activities have been envisioned for fullerenes and some of them seem to be
very promising. The lack of solubility in biologically friendly environments is the major …

Oxidative stress-mediated hemolytic activity of solvent exchange-prepared fullerene (C60) nanoparticles

A Trpkovic, B Todorovic-Markovic, D Kleut… - …, 2010 - iopscience.iop.org
The present study investigated the hemolytic properties of fullerene (C 60) nanoparticles
prepared by solvent exchange using tetrahydrofuran (nC 60 THF), or by mechanochemically …

Fullerenes as photosensitizers in photodynamic therapy

P Mroz, GP Tegos, H Gali, T Wharton, T Sarna… - Medicinal chemistry and …, 2008 - Springer
Fullerenes are a class of closed-cage nanomaterials made exclusively from carbon atoms. A
great deal of attention has been focused on developing medical uses of these unique …

Maximizing safe design of engineered nanomaterials: the NIH and NIEHS research perspective

SS Tinkle - Wiley Interdisciplinary Reviews: Nanomedicine and …, 2010 - Wiley Online Library
Estimating potential risk of an emerging technology as its products are being developed
offers the greatest potential for success of the technology. The National Nanotechnology …