Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

Alcohol use produces wide-ranging and diverse effects on the central nervous system. It
influences intracellular signaling mechanisms, leading to changes in gene expression …

The Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium has focused on
the impact of adolescent binge drinking on brain development, particularly on effects that …

Alcohol acts on numerous cellular and molecular targets to regulate neuronal
communication within the brain. Chronic alcohol exposure and acute withdrawal generate …

Adolescence is the transitional period between childhood and adulthood, during which
extensive brain development occurs. Since this period also overlaps with the initiation of …

A key feature of compulsive alcohol drinking is continuing to drink despite negative
consequences. To examine the changes in neural activity that underlie this behavior …

Background Adolescent intermittent ethanol (AIE) exposure is an emerging risk factor for
adult psychopathology, such as anxiety disorders. Enhancer RNAs (eRNAs) are short …

Binge drinking during adolescence is highly prevalent despite increasing evidence of its
long-term impact on behaviors associated with modulation of behavioral flexibility by the …

Alcohol use disorder (AUD) affects all sexes, however women who develop AUD may be
particularly susceptible to cravings and other components of the disease. While many brain …