This review seeks to offer a broad perspective that encompasses an understanding of the
drug product attributes affected by active pharmaceutical ingredient (API) physical …

The fundamental crystal science underpinning the industrial crystallisation of organic
materials is reviewed from molecular, intermolecular (synthonic) and crystallographic …

We trace the evolution of crystal interface during the solvothermal synthesis of metal-organic
frameworks (MOFs) in flow cell by in situ dark-field microscope. Precise measurement of the …

The crystallization of α-p-aminobenzoic acid (p ABA) from mixed solutions in ethanol (EtOH)
and nitromethane (NMe) is reported. From solutions with compositions> 60 wt% NMe, the …

The crystal growth kinetics of a proprietary active pharmaceutical ingredient (API) was
investigated by isothermal seeded batch de-supersaturation experiments in solvent mixtures …

Understanding the growth of needle-shaped molecular crystals and the factors that influence
the needle morphology is not only a fundamental research question but is also important in …

The key intermolecular (synthonic) interactions, crystal morphology, and surface interfacial
stability of the anti-inflammatory drug RS-ibuprofen are examined in relation to its bulk …

This study investigates the effect of ibuprofen particle morphology and surface properties on
its tendency to auto-agglomerate. Four diverse particle morphologies were produced by …

Crystal growth, which is one of the fundamental steps in the crystallization process, can
affect the morphology of crystals which will further affect physicochemical properties of …

This study investigated the effects of polymeric additives such as hydroxypropyl methyl
cellulose (HPMC) and polyvinylpyrrolidone (PVP) on the growth kinetics of naproxen crystal …