Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina
S Schnichels, F Paquet-Durand, M Löscher… - Progress in retinal and …, 2021 - Elsevier
For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …
Polysaccharide-based hydrogels for medical devices, implants and tissue engineering: A review
Hydrogels are highly biocompatible biomaterials composed of crosslinked three-
dimensional networks of hydrophilic polymers. Owing to their natural origin, polysaccharide …
dimensional networks of hydrophilic polymers. Owing to their natural origin, polysaccharide …
Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature
C Leichner, M Jelkmann… - Advanced Drug Delivery …, 2019 - Elsevier
Thiolated polymers designated “thiomers” are obtained by covalent attachment of thiol
functionalities on the polymeric backbone of polymers. In 1998 these polymers were first …
functionalities on the polymeric backbone of polymers. In 1998 these polymers were first …
Polymeric hydrogels as a vitreous replacement strategy in the eye
Vitreous endo-tamponades are commonly used in the treatment of retinal detachments and
tears. They function by providing a tamponading force to support the retina after retina …
tears. They function by providing a tamponading force to support the retina after retina …
Stable oxime-crosslinked hyaluronan-based hydrogel as a biomimetic vitreous substitute
Vitreous substitutes are clinically used to maintain retinal apposition and preserve retinal
function; yet the most used substitutes are gases and oils which have disadvantages …
function; yet the most used substitutes are gases and oils which have disadvantages …
A long-acting curcumin nanoparticle/in situ hydrogel composite for the treatment of uveal melanoma
Uveal melanoma (UM) is the most common primary intraocular tumor in adults with high
mortality. In order to improve prognosis and survival of UM patients, it is critical to inhibit …
mortality. In order to improve prognosis and survival of UM patients, it is critical to inhibit …
Thiolated hyaluronic acid as versatile Mucoadhesive polymer: from the chemistry behind to product developments—what are the capabilities?
J Griesser, G Hetényi, A Bernkop-Schnürch - Polymers, 2018 - mdpi.com
Within the last decade, intensive research work has been conducted on thiolated hyaluronic
acids (HA-SH). By attaching sulfhydryl ligands onto naturally occurring hyaluronic acid …
acids (HA-SH). By attaching sulfhydryl ligands onto naturally occurring hyaluronic acid …
High molecular weight hyper-branched PCL-based thermogelling vitreous endotamponades
Vitreous endotamponades play essential roles in facilitating retina recovery following
vitreoretinal surgery, yet existing clinically standards are suboptimal as they can cause …
vitreoretinal surgery, yet existing clinically standards are suboptimal as they can cause …
Alginate-and hyaluronic acid–based hydrogels as vitreous substitutes: an in vitro evaluation
A Schulz, A Rickmann, S Wahl… - … Vision Science & …, 2020 - tvst.arvojournals.org
Methods: Biopolymeric hydrogels based on high-molecular alginate (0.5% and 1.0%) and
hyaluronic acid (1.0% and Healaflow) were compared with extracted human vitreous bodies …
hyaluronic acid (1.0% and Healaflow) were compared with extracted human vitreous bodies …
Mucoadhesive micro-/nano carriers in ophthalmic drug delivery: an overview
The eye is a challenging organ for ophthalmic drug delivery due to the barriers associated
with the anterior and posterior segments like nasolacrimal drainage, blinking, induced …
with the anterior and posterior segments like nasolacrimal drainage, blinking, induced …