Genetics of cholesterol-related genes in metabolic syndrome: a review of current evidence

SK Wong, FF Ramli, A Ali, NI Ibrahim - Biomedicines, 2022 - mdpi.com
Metabolic syndrome (MetS) refers to a cluster of metabolic dysregulations, which include
insulin resistance, obesity, atherogenic dyslipidemia and hypertension. The complex …

Clinical management of dyslipidaemia associated with combination antiretroviral therapy in HIV-infected patients

L Calza, V Colangeli, R Manfredi, I Bon… - Journal of …, 2016 - academic.oup.com
The introduction of potent combination antiretroviral therapy (cART) has had a remarkable
impact on the natural history of HIV infection, leading to a dramatic decline in the mortality …

Associations of the APOB rs693 and rs17240441 polymorphisms with plasma APOB and lipid levels: a meta-analysis

C Niu, Z Luo, L Yu, Y Yang, Y Chen, X Luo… - Lipids in health and …, 2017 - Springer
Background The associations of the apolipoprotein B gene (APOB) rs693 and rs17240441
polymorphisms with plasma levels of APOB and lipids have been widely explored, but the …

HIV-associated lipodystrophy: a review from a Brazilian perspective

MD Alves, C Brites, E Sprinz - Therapeutics and clinical risk …, 2014 - Taylor & Francis
The prognosis of human immunodeficiency virus (HIV)-infected individuals has dramatically
improved worldwide since the introduction of highly antiretroviral therapy. Nevertheless …

Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar

D Al‐Sharshani, D Velayutham… - … Genetics & Genomic …, 2023 - Wiley Online Library
Background Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases
(CVDs), type 2 diabetes mellitus (T2DM), and non‐alcoholic fatty liver disease (NAFLD) …

Polymorphisms associated with renal adverse effects of antiretroviral therapy in a Southern Brazilian HIV cohort

IM da Rocha, AS Gasparotto… - Pharmacogenetics …, 2015 - journals.lww.com
Objective This study evaluated the impact of seven single nucleotide polymorphisms in five
candidate genes (ABCB1, ABCC2, ABCC4, SLC22A6, and SLC22A11) in relation to …

Pharmacogenetic considerations in the treatment of HIV

VS Mattevi, CFS Tagliari - Pharmacogenomics, 2017 - Taylor & Francis
After the introduction of highly active antiretroviral therapy in the 1990s, the perception of the
diagnosis of HIV infection gradually shifted from a 'death sentence'to a chronic disease …

Investigation of SIRT1 gene variants in HIV-associated lipodystrophy and metabolic syndrome

CFS Tagliari, CN de Oliveira, GM Vogel… - … and Molecular Biology, 2020 - SciELO Brasil
HIV-infected individuals on chronic use of highly active antiretroviral therapy (HAART) are
more likely to develop adipose tissue and metabolic disorders, such as lipodystrophy (LD) …

Association of single nucleotide polymorphisms with dyslipidemia in antiretroviral exposed HIV patients in a Ghanaian population: A case-control study

C Obirikorang, E Acheampong, L Quaye, J Yorke… - PLoS …, 2020 - journals.plos.org
Dyslipidemia is a potential complication of long-term usage of antiretroviral therapy (ART)
and also known to be associated with genetic factors. The host genetic variants associated …

[HTML][HTML] Apolipoprotein B gene polymorphisms and dyslipidemia in HIV infected adult Zimbabweans

V Kodogo, DT Zhou, O Oektedalen, K Duri… - The open AIDS …, 2016 - ncbi.nlm.nih.gov
Background: Dyslipidemia does not occur in all HIV-infected or antiretroviral therapy-
experienced patients suggesting role of host genetic factors but there is paucity of data on …