This review provides an in-depth exploration of the mechanisms and applications of
transcutaneous auricular vagus nerve stimulation (taVNS) in treating disorders of …

The vagus nerve vitally connects the brain and body to coordinate digestive,
cardiorespiratory, and immune functions. Its efferent neurons, which project their axons from …

Bioelectronic therapies modulating the vagus nerve are promising for cardiovascular,
inflammatory, and mental disorders. Clinical applications are however limited by side-effects …

Vagal fibers travel inside fascicles and form branches to innervate organs and regulate
organ functions. Existing vagus nerve stimulation (VNS) therapies activate vagal fibers non …

BACKGROUND: Inflammation is pathogenically implicated in pulmonary arterial
hypertension; however, it has not been adequately targeted therapeutically. We investigated …

Focused ultrasound stimulation (FUS) activates mechanosensitive ion channels and is
emerging as a method of noninvasive neuromodulation. In preclinical studies, FUS of the …

Background Vagal reflexes regulate homeostasis in visceral organs and systems through
afferent and efferent neurons and nerve fibers. Small, unmyelinated, C-type afferents …

Introduction Despite detailed characterization of fascicular organization of somatic nerves,
the functional anatomy of fascicles evident in human and large mammal cervical vagus …

Background Autonomic nerve stimulation is used as a treatment for a growing number of
diseases. We have previously demonstrated that application of efferent vagus nerve …

Implantable neuroelectronic interfaces have gained significant importance in long-term brain–
computer interfacing and neuroscience therapy. However, due to the mechanical and …