[HTML][HTML] The role of bacterial ATP-binding cassette (ABC) transporters in pathogenesis and virulence: Therapeutic and vaccine potential

AA Akhtar, DPJ Turner - Microbial pathogenesis, 2022 - Elsevier
The ATP-binding cassette (ABC) transporter superfamily is found in all domains of life,
facilitating critical biological processes through the translocation of a wide variety of …

ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies

HS Garmory, RW Titball - Infection and immunity, 2004 - Am Soc Microbiol
ATP-binding cassette (ABC) transporters are widespread among living organisms and
comprise one of the largest protein families. For example, components of ABC transporters …

Role of Toll-Like Receptor 4 in Induction of Cell-Mediated Immunity and Resistance to Brucella abortus Infection in Mice

MA Campos, GMS Rosinha, IC Almeida… - Infection and …, 2004 - Am Soc Microbiol
Initial host defense to bacterial infection is executed by innate immunity, and therefore the
main goal of this study was to examine the contribution of Toll-like receptors (TLRs) during …

Comparison of OG1RF and an Isogenic fsrB Deletion Mutant by Transcriptional Analysis: the Fsr System of Enterococcus faecalis Is More than the Activator of …

A Bourgogne, SG Hilsenbeck, GM Dunny… - Journal of …, 2006 - Am Soc Microbiol
ABSTRACT The FsrABC system of Enterococcus faecalis controls the expression of
gelatinase and a serine protease via a quorum-sensing mechanism, and recent studies …

The role of ATP-binding cassette transporters in bacterial pathogenicity

VG Lewis, MP Ween, CA McDevitt - Protoplasma, 2012 - Springer
The ATP-binding cassette transporter superfamily is present in all three domains of life. This
ubiquitous class of integral membrane proteins have diverse biological functions, but their …

Pneumococcal surface adhesin A (PsaA): a review

G Rajam, JM Anderton, GM Carlone… - Critical reviews in …, 2008 - Taylor & Francis
Pneumococcal surface adhesin A (PsaA) is a surface-exposed common 37-kilodalton multi-
functional lipoprotein detected on all known serotypes of Streptococcus pneumoniae. This …

Role of AFR1, an ABC Transporter-Encoding Gene, in the In Vivo Response to Fluconazole and Virulence of Cryptococcus neoformans

M Sanguinetti, B Posteraro, M La Sorda… - Infection and …, 2006 - Am Soc Microbiol
We have recently demonstrated that upregulation of the ATP binding cassette (ABC)
transporter-encoding gene AFR1 in Cryptococcus neoformans is involved in the in vitro …

Brucella pathogenesis, genes identified from random large-scale screens

RM Delrue, P Lestrate, A Tibor… - FEMS microbiology …, 2004 - academic.oup.com
Pathogenicity islands, specialized secretion systems, virulence plasmids, fimbriae, pili,
adhesins, and toxins are all classical bacterial virulence factors. However, many of these …

ATP-binding cassette (ABC) import systems of Mycobacterium tuberculosis: target for drug and vaccine development

DK Soni, SK Dubey, R Bhatnagar - Emerging Microbes & Infections, 2020 - Taylor & Francis
Nutrient procurement specifically from nutrient-limiting environment is essential for
pathogenic bacteria to survive and/or persist within the host. Long-term survival or persistent …

Deletion of znuA Virulence Factor Attenuates Brucella abortus and Confers Protection against Wild-Type Challenge

X Yang, T Becker, N Walters… - Infection and immunity, 2006 - Am Soc Microbiol
ABSTRACT znuA is known to be an important factor for survival and normal growth under
low Zn2+ concentrations for Escherichia coli, Haemophilus spp., Neisseria gonorrhoeae …