Aminothiophenes are important five-membered heterocyclic building blocks in organic
synthesis, and the chemistry of these small molecules is still developing based on the …

Energy metabolism is a universal process occurring in all life forms. In Mycobacterium
tuberculosis (Mtb), energy production is carried out in two possible ways, oxidative …

Abstract Ethyl 2‐acrylamido‐4, 5, 6, 7‐tetrahydrobenzo [b] thiophene‐3‐carboxylate as well
as its corresponding bis‐derivatives, 5–10, with aliphatic linkers were synthesized, fully …

Tuberculosis (TB) remains a serious health problem responsible to cause millions of deaths
annually. The scenario becomes alarming when it is evaluated that the number of new drugs …

Abstract Alanine dehydrogenase (AlaDH)(EC 1.4. 1.1) is a microbial enzyme that catalyzes
a reversible conversion of L-alanine to pyruvate. Inter-conversion of alanine and pyruvate by …

Developing new, more effective antibiotics against resistant Mycobacterium tuberculosis that
inhibit its essential proteins is an appealing strategy for combating the global tuberculosis …

This review provides an overview of the applications of α-halogenoacetamides in domino
and cycloaddition reactions. α-Halogenoacetamides are versatile building blocks that can …

Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the infectious disease
responsible for the highest number of deaths worldwide. Herein, 22 new N-oxide-containing …

ERK1 and ERK5 are proposed to have pivotal roles in several types of cancer. Under some
circumstance, ERK5 may provide a common bypass route, which rescues proliferation upon …

Tuberculosis caused by the bacterium, Mycobacterium tuberculosis (Mtb), continues to
remain one of the most devastating infectious diseases afflicting humans. Although there are …