Paediatric functional abdominal pain disorders, currently referred to as disorders of gut–
brain interaction, comprise irritable bowel syndrome, functional dyspepsia, abdominal …

This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …

The placebo effect has often been considered a nuisance in basic and particularly clinical
research. This view has gradually changed in recent years due to deeper insight into the …

Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

Cannabinoids in the Treatment of Epilepsy | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Background Plaque psoriasis affects children and adults, but treatment options for paediatric
psoriasis are limited. Objectives To evaluate the efficacy and safety of ixekizumab (IXE), a …

Placebo effects in clinical trials have sparked an interest in the placebo phenomenon, both
in randomized controlled trials (RCTs) and in experimental gastroenterology. RCTs have …

Several lines of emerging data point to an imbalance between neuronal excitation and
inhibition in at least a subgroup of individuals with autism spectrum disorder (ASD) …

The issue of placebo response and the extent of its effect on psychotherapy is complex for
two specific reasons: i) Current standards for drug trials, eg, true placebo interventions …

Importance Migraine is one of the most common neurologic disorders in children and
adolescents. However, a quantitative comparison of multiple preventive pharmacologic …