Supersaturation-based drug delivery systems: strategy for bioavailability enhancement of poorly water-soluble drugs

A Sharma, K Arora, H Mohapatra, RK Sindhu, M Bulzan… - Molecules, 2022 - mdpi.com
At present, the majority of APIs synthesized today remain challenging tasks for formulation
development. Many technologies are being utilized or explored for enhancing solubility …

Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin

T Şenyiğit, F Sonvico, S Barbieri, Ö Özer, P Santi… - Journal of Controlled …, 2010 - Elsevier
In this study, clobetasol-17-propionate (CP) loaded lecithin/chitosan nanoparticles were
studied with special attention to the transport of the active agent across the skin in vitro …

Development of a standardized dissolution test method for inhaled pharmaceutical formulations

YJ Son, JT McConville - International journal of pharmaceutics, 2009 - Elsevier
The aim of this research was to investigate a potential standardized test method to
characterize the dissolution properties of formulations intended for pulmonary delivery. A …

Amelioration of cerebral ischemia–reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin

T Ishii, T Asai, D Oyama, T Fukuta, N Yasuda… - Journal of controlled …, 2012 - Elsevier
Cerebral ischemia–reperfusion (I/R) injury induces secondary cerebral damage. As drugs
for treating this type of injury have shown poor efficacy and adverse side effects in clinical …

Noninvasive and persistent transfollicular drug delivery system using a combination of liposomes and iontophoresis

K Kajimoto, M Yamamoto, M Watanabe… - International journal of …, 2011 - Elsevier
Iontophoresis is a promising technique for enhancing transdermal administration of charged
drugs. However, conventional iontophoresis is not sufficient for effective delivery of large …

Propylene glycol-embodying deformable liposomes as a novel drug delivery carrier for vaginal fibrauretine delivery applications

WZ Li, XL Hao, N Zhao, WX Han, XF Zhai… - Journal of Controlled …, 2016 - Elsevier
The purpose of this work was to develop and characterize the fibrauretine (FN) loaded
propylene glycol-embodying deformable liposomes (FDL), and evaluate the …

Transdermal drug delivery system: An overview

SA Nagdev, O Agrawal… - Research Journal of …, 2022 - indianjournals.com
From the past three decades there are huge changes and developments in formulation
technology. Innovations in drug delivery systems are not only associated with the …

Topical application of liposomal cobalamin hydrogel for atopic dermatitis therapy

SH Jung, YS Cho, SS Jun, JS Koo… - Die Pharmazie-An …, 2011 - ingentaconnect.com
Topical vitamin B12 was shown to be effective for atopic dermatitis. However, vitamin B12
itself is light sensitive and has low skin permeability, thus reducing its therapeutic …

In vivo hair growth promotion effects of cosmetic preparations containing hinokitiol-loaded poly(ε-caprolacton) nanocapsules

SL Hwang, JC Kim - Journal of microencapsulation, 2008 - Taylor & Francis
Nanocapsules containing hinokitiol (HKL) were prepared by an emulsion-diffusion method.
In an emulsification step in preparing nanocapsules, cetyltrimethylamonium chloride (CTAC) …

Drug “supersaturation” states induced by polymeric micelles and liposomes: A mechanistic investigation into permeability enhancements

M Di Cagno, B Luppi - European Journal of Pharmaceutical Sciences, 2013 - Elsevier
The objective of this study was to investigate if the increase in apparent solubility induced by
liposomalization or micellization of the poorly soluble drug hydrocortisone (HC) would lead …