Glutamate-mediated excitotoxicity is an important mechanism leading to post ischemic
stroke damage. After acute stroke, the sudden reduction in cerebral blood flow is most …

Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS)
which initiates rapid signal transmission in the synapse before its re-uptake into the …

Diabetes mellitus is a chronic metabolic disease which is a serious global problem. In 2010
an estimated 285 million people had diabetes and within the next 20 years this value is …

Pentacyclic triterpenoids including the oleanane, ursane and lupane groups are widely
distributed in many medicinal plants, such as Glycyrrhiza species, Gymnema species …

Terpenes and terpenoids are the largest groups of plant secondary metabolites. However,
unlike polyphenols, they are rarely associated with geroprotective properties. Here we …

Although being a physiologically important excitatory neurotransmitter, glutamate plays a
pivotal role in various neurological disorders including ischemic neurological diseases. Its …

Prevention of epilepsy is a great unmet need. Acute central nervous system (CNS) insults
such as traumatic brain injury (TBI), cerebrovascular accidents (CVA), and CNS infections …

In the present study, we isolated seven compounds from olive mill wastes (OMW), one of
them being novel, and investigated their antidiabetic potential through inhibition of α …

Maslinic acid is a pentacyclic triterpene found in a variety of natural sources, ranging from
herbal remedies used in traditional Asian medicine to edible vegetables and fruits present in …

Maslinic acid (MA) is a pentacyclic triterpene acid, which exists in many plants, including
olive, and is highly safe for human beings. In recent years, it has been reported that MA has …