Summary Fragile X Syndrome (FXS) is a commonly inherited form of intellectual disability and one of the leading genetic causes for autism spectrum disorder. Clinical symptoms of …
DD Hatton, J Sideris, M Skinner… - American journal of …, 2006 - Wiley Online Library
We examined autistic behavior in a cross‐sectional sample of 179 children with fragile X syndrome (FXS) and a longitudinal subset of 116 children using the Childhood Autism …
Fragile X syndrome (FXS) is the most common single gene cause of autism and intellectual disabilities. Humans with FXS exhibit increased anxiety, sensory hypersensitivity, seizures …
RL Stornetta, JJ Zhu - The Neuroscientist, 2011 - journals.sagepub.com
The Ras family GTPases (Ras, Rap1, and Rap2) and their downstream mitogen-activated protein kinases (ERK, JNK, and p38MAPK) and PI3K signaling cascades control various …
K Cornish, J Turk, R Hagerman - Journal of Intellectual …, 2008 - Wiley Online Library
Fragile X syndrome is the world's most common hereditary cause of intellectual disability in men and to a lesser extent in women. The disorder is caused by the silencing of a single …
Many males with FXS meet criteria for ASD. This study was designed to (1) describe ASD symptoms in adolescent and young adult males with FXS (n= 44) and (2) evaluate the …
H Hu, Y Qin, G Bochorishvili, Y Zhu… - Journal of …, 2008 - Soc Neuroscience
Fragile X syndrome, caused by the loss of FMR1 gene function and loss of fragile X mental retardation protein (FMRP), is the most commonly inherited form of mental retardation. The …
A McDuffie, AJ Thurman, RJ Hagerman… - Journal of autism and …, 2015 - Springer
Symptoms of autism are frequent in males with fragile X syndrome (FXS), but it is not clear whether symptom profiles differ from those of nonsyndromic ASD. Using individual item …
M Raspa, AC Wheeler, C Riley - Pediatrics, 2017 - publications.aap.org
OBJECTIVES: The purpose of this systematic literature review is to describe what is known about fragile X syndrome (FXS) and to identify research gaps. The results can be used to …