The prognosis of cervical patients significantly decreases as the cancer metastasizes to
other parts of the body. The epithelial to mesenchymal transition (EMT) plays an important …

During the progression of epithelial cancer, cells usually lose epithelial characteristic
features and gain a mesenchymal phenotype. Cervical cancer is a common female …

Oral squamous cell carcinoma is a challenging oncology problem. A reliable biomarker for
metastasis or high-risk prognosis in oral cancer patients remains undefined. Using …

Purpose: Acquisition of epithelial-mesenchymal transition (EMT) by primary carcinoma cells
is associated with disrupted epithelial integrity, local invasion, and ultimately metastasis …

Mitotic spindle orientation can influence tissue organization and vice versa. Cells orient their
spindles by rotating them parallel or perpendicular to the cell–and hence the tissue–axis …

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), is negatively
correlated with tumor progression in multiple neoplasms, being a promising new target for …

Abstract Treatment failure is one of the main hurdles in treating cervical cancer, despite
significant breakthroughs in both conventional and targeted therapy. The one-year survival …

During tumor progression cells acquire an altered metabolism, either as a cause or as a
consequence of an increased need of energy and nutrients. All four major classes of …

Transition between epithelial and mesenchymal states is a feature of both normal
development and tumor progression. We report that expression of chloride channel …

Highlights•SLCs play a key part in the metabolically driven tumor growth and
metastasis.•SLCs can exert both tumor-promoting as well as suppressive functions in …