Human papillomaviruses as infectious agents in gynecological cancers. Oncogenic properties of viral proteins

DA Haręża, JR Wilczyński, E Paradowska - International journal of …, 2022 - mdpi.com
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

Caught up in a Wnt storm: Wnt signaling in cancer

RH Giles, JH Van Es, H Clevers - … et Biophysica Acta (BBA)-Reviews on …, 2003 - Elsevier
The Wnt signaling pathway, named for its most upstream ligands, the Wnts, is involved in
various differentiation events during embryonic development and leads to tumor formation …

Signaling pathways in HPV‐associated cancers and therapeutic implications

J Chen - Reviews in medical virology, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) are small double‐stranded circular DNA viruses with 8 kb
genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have …

The role of signaling pathways in cervical cancer and molecular therapeutic targets

J Manzo-Merino, A Contreras-Paredes… - Archives of medical …, 2014 - Elsevier
Cervical cancer is a public health issue in developing countries. Although the Pap smear
and colposcopy remain the major strategies for detection, most cases are diagnosed in the …

[PDF][PDF] Wilczy nski, JR; Paradowska, E. Human papillomaviruses as infectious agents in gynecological cancers. oncogenic properties of viral proteins

DA Hareza - Int. J. Mol. Sci, 2022 - pdfs.semanticscholar.org
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

[HTML][HTML] The lncRNA LINC00675 regulates cell proliferation, migration, and invasion by affecting Wnt/β-catenin signaling in cervical cancer

S Ma, X Deng, Y Yang, Q Zhang, T Zhou… - Biomedicine & …, 2018 - Elsevier
Cervical cancer is one of the most common gynecological malignancies worldwide.
Recently, the long noncoding RNAs (lncRNAs) have been shown to play essential roles in …

Clinical significance and prognosis value of Wnt signaling pathway in cervical cancer

A Bahrami, M Hasanzadeh… - Journal of cellular …, 2017 - Wiley Online Library
Cervical cancer is among the most commonly diagnosed cancer in women, supporting the
need for identification of novel prognostic and predictive biomarkers to predict the risk of …

AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity

HT Kwan, DW Chan, PCH Cai, CSL Mak, MMH Yung… - PLoS …, 2013 - journals.plos.org
Recent evidence has suggested that AMPK activators may be applied as therapeutic drugs
in suppressing cancer cell growth. However, the molecular mechanism of their suppressive …

Abnormal distribution of E-cadherin and β-catenin in different histologic types of cancer of the uterine cervix

MA Rodríguez-Sastre, L González-Maya… - Gynecologic …, 2005 - Elsevier
OBJECTIVE: The goal of this study was to analyze the cellular distribution and possible
alterations of β-catenin and E-cadherin proteins in different histologic types of uterine …

[HTML][HTML] HPV16 E6 augments Wnt signaling in an E6AP-dependent manner

H Lichtig, DA Gilboa, A Jackman, P Gonen… - Virology, 2010 - Elsevier
In this study we investigated the effect of HPV16 E6 on the Wnt/β-catenin oncogenic
signaling pathway. Luciferase reporter assays indicated that ectopically expressed E6 …