Intrinsically disordered proteins and protein regions (IDRs) are abundant in eukaryotic
proteomes and play a wide variety of essential roles. Instead of folding into a stable …

Higher eukaryotes' life is impossible without copper redox activity and, literally, every breath
we take biochemically demonstrates this. However, this dependence comes at a …

Copper, manganese, and iron are vital elements required for the appropriate development
and the general preservation of good health. Additionally, these essential metals play key …

It is now well established that the blood-clotting protein fibrinogen can polymerise into an
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …

The aggregation and accumulation of amyloidogenic peptides and proteins are observed as
pathological features in the brains of patients suffering from neurodegenerative disorders …

The process of aggregation of proteins and peptides is dependent on the concentration of
proteins, and the rate of aggregation can be altered by the presence of metal ions, but this …

Liquid–liquid phase separation (LLPS) appears to be a newly appreciated aspect of the
cellular organization of biomolecules that leads to the formation of membraneless …

In this review we give an updated outlook of the reactivity of catecholamines, particularly
dopamine, and the redox effects produced by their interaction with copper (II) and dioxygen …

Trace elements such as iron (Fe), zinc (Zn), copper (Cu), and manganese (Mn) are
absorbed from food via the gastrointestinal tract, transported into the brain, and play central …

Liquid-liquid phase separation (LLPS) is a rapidly growing research focus due to numerous
demonstrations that many cellular proteins phase-separate to form biomolecular …