Resveratrol is a naturally occurring stilbene endowed with multiple health-promoting effects.
It is produced by certain plants including several dietary sources such as grapes, apples …

Pressure ulcers are preventable, yet highly prevalent, chronic wounds that have significant
patient morbidity and high healthcare costs. Like other chronic wounds, they are …

The aim of the present study was to determine the protective effects of resveratrol on a rat
model of osteoporosis and examine the associated mechanisms of its action. Rats were …

Objective: Sarcopenia or frailty is common among patients with chronic kidney disease
(CKD). The protein-bound uremic toxin indoxyl sulfate (IS) is associated with frailty. IS …

Background Inflammation plays an important role in thrombus formation, and Sirtuin 1
(SIRT1) negatively regulates inflammation via deacetylating nuclear factor-kappa B …

Mitochondrial dysfunction is involved in the pathology of Parkinson's disease, an age-
associated neurodegenerative disorder. Phosphatase and tensin homolog (PTEN)-induced …

Muscle injuries frequently occur in contact sports events. The current treatment options for
soft tissue injuries remain suboptimal and often result in delayed or incomplete recovery of …

The aim of this study was to investigate whether the SIRT1 exerts neuroprotective effects by
attenuating cerebral ischemia/reperfusion-induced injury (CIRI) via targeting p53/microRNA …

Skeletal muscle (SkM) is essential for body movement, energy metabolism, and material
metabolism, and directly influences the quality of human life. Aging, chronic diseases, and …

Sodium salt of deoxyribonucleic acid (DNA), Derinat, isolated from the soft roes of Russian
sturgeon, has been utilized as an immunomodulator for the treatment of reactive oxygen …