[HTML][HTML] Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring

L Chen, Y Zhang, YX Zhang, WL Wang, DM Sun… - Journal of …, 2024 - Elsevier
Tyrosine kinase inhibitors (TKIs) have emerged as the first-line small molecule drugs in
many cancer therapies, exerting their effects by impeding aberrant cell growth and …

Homogeneous liquid–liquid microextraction of organic compounds

SG Dmitrienko, VV Apyari, MV Gorbunova… - Journal of Analytical …, 2020 - Springer
Published data on various versions of the homogeneous liquid–liquid microextraction
(HLLME) of organic compounds are generalized and systematized, and a classification of …

Sensitivity enhancement in capillary electrophoresis and their applications for analyses of pharmaceutical and related biochemical substances

L Suntornsuk, O Anurukvorakun - Electrophoresis, 2022 - Wiley Online Library
This review aims to illustrate sensitivity enhancement methods in capillary electrophoresis
(CE) and their applications for pharmaceutical and related biochemical substance analyses …

Simultaneous determination of 13 nitrosamine impurities in biological medicines using salting-out liquid-liquid extraction coupled with liquid chromatography tandem …

F Luo, Y Liu, Y Xie, W Hou, L Zhang, Z Zhang - Journal of Pharmaceutical …, 2022 - Elsevier
Nitrosamine impurities are being detected in various pharmaceutical products recently.
However, no analytical method is provided for biopharmaceuticals. In present work, a salting …

Melt-blown polypropylene nonwoven as an efficient and eco-economic sorbent for pipette tip micro-solid phase extraction for the determination of tyrosine kinase …

J Ye, Y Zheng, X Li, X Jiang, D Chen - Analytica Chimica Acta, 2024 - Elsevier
Background The detection of tyrosine kinase inhibitors (TKIs) in biological fluids is essential
due to their critical role in cancer therapy and the variability in individual drug metabolism …

An automated accelerated salting-out assisted solvent extraction (A-ASASE) of stilbenoids from Vitis vinifera L. branches: False proof or a proof of concept?

OS Ahmed, F Tahanout, G Marti-Mestres, JF Weber… - Talanta, 2024 - Elsevier
An automated accelerated salting-out assisted solvent extraction (A-ASASE) was
developed. This approach made full use of the advantages of both the accelerated solvent …

A fully automated on-line salting-out assisted liquid-liquid extraction capillary electrophoresis methodology: Application to tyrosine kinase inhibitors in human plasma

OS Ahmed, Y Ladner, J Xia, J Montels, L Philibert… - Talanta, 2020 - Elsevier
A fully automated analytical methodology combining salting-out assisted liquid-liquid
extraction (SALLE) and capillary electrophoresis (CE) for the analysis of three Tyrosine …

A low-voltage electro-membrane extraction for quantification of imatinib and sunitinib in biological fluids

AZ Moghaddam, AE Bameri, MR Ganjali, M Alexovič… - Bioanalysis, 2021 - Taylor & Francis
Aim: Hollow-fiber-based supported liquid membrane was modified utilizing nanostructures
such as graphite, graphene oxide or nitrogen-doped graphene oxide, for electro-membrane …

Determination of Tyrosine Kinase Inhibitors via Capillary Electrophoresis with Tandem Mass Spectrometry and Online Stacking Preconcentration

J Petr - Pharmaceuticals, 2023 - mdpi.com
Capillary electrophoresis connected with tandem mass spectrometry was employed for the
development of a method for determination of various tyrosine kinase inhibitors in plasma …

Advances in screening enzyme inhibitors by capillary electrophoresis

WF Wang, JL Yang - Electrophoresis, 2019 - Wiley Online Library
Capillary electrophoresis (CE) has attracted lots of attention due to its simplicity, low sample
consumption, low solvent volume, high resolution, and high speed. Based on these …