Human milk oligosaccharides: health benefits, potential applications in infant formulas, and pharmacology

M Wiciński, E Sawicka, J Gębalski, K Kubiak… - Nutrients, 2020 - mdpi.com
The first months of life are a special time for the health development and protection of
infants. Breastfeeding is the natural and best way of feeding an infant, and positively …

Shaping the gut microbiota by breastfeeding: the gateway to allergy prevention?

LWJ Van den Elsen, J Garssen, R Burcelin… - Frontiers in …, 2019 - frontiersin.org
Evidence is accumulating that demonstrates the importance of the gut microbiota in health
and diseases such as allergy. Recent studies emphasize the importance of the “window of …

Comparison of gut microbiota in exclusively breast-fed and formula-fed babies: a study of 91 term infants

J Ma, Z Li, W Zhang, C Zhang, Y Zhang, H Mei… - Scientific reports, 2020 - nature.com
To compare gut microbiota of healthy infants that were exclusively breast-fed or formula-fed,
we recruited 91 infants, who were assigned into three different groups and fed by breast milk …

Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response

KH Antunes, JL Fachi, R de Paula, EF da Silva… - Nature …, 2019 - nature.com
Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality
in infants< 2 years-old. Here we describe that high-fiber diet protects mice from RSV …

Functional effects of human milk oligosaccharides (HMOs)

M Dinleyici, J Barbieur, EC Dinleyici, Y Vandenplas - Gut Microbes, 2023 - Taylor & Francis
Human milk oligosaccharides (HMOs) are the third most important solid component in
human milk and act in tandem with other bioactive components. Individual HMO levels and …

An overview on fecal branched short-chain fatty acids along human life and as related with body mass index: associated dietary and anthropometric factors

D Rios-Covian, S González, AM Nogacka… - Frontiers in …, 2020 - frontiersin.org
Short-chain fatty acids (SCFA) are the main bacterial products of the catabolism of
carbohydrates and proteins in the gut, and their role is essential in host–microbiota …

The role of gut microbiota and environmental factors in type 1 diabetes pathogenesis

S Dedrick, B Sundaresh, Q Huang, C Brady… - Frontiers in …, 2020 - frontiersin.org
Type 1 Diabetes (T1D) is regarded as an autoimmune disease characterized by insulin
deficiency resulting from destruction of pancreatic β-cells. The incidence rates of T1D have …

Gut microbiome immaturity and childhood acute lymphoblastic leukaemia

I Peppas, AM Ford, CL Furness, MF Greaves - Nature Reviews Cancer, 2023 - nature.com
Acute lymphoblastic leukaemia (ALL) is the most common cancer of childhood. Here, we
map emerging evidence suggesting that children with ALL at the time of diagnosis may have …

Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis

KH Antunes, RT Stein, C Franceschina, EF da Silva… - …, 2022 - thelancet.com
Background Gut microbiota-derived short-chain fatty-acid (SFCA) acetate protects mice
against RSV A2 strain infection by increasing interferon-β production and expression of …

Infant gut microbiota colonization: influence of prenatal and postnatal factors, focusing on diet

C Suárez-Martínez, M Santaella-Pascual… - Frontiers in …, 2023 - frontiersin.org
Maternal microbiota forms the first infant gut microbial inoculum, and perinatal factors (diet
and use of antibiotics during pregnancy) and/or neonatal factors, like intra partum antibiotics …