Biomarkers to predict the clinical efficacy of bevacizumab in cancer
Bevacizumab is a monoclonal antibody against vascular endothelial growth factor that has
antiangiogenic activity and improves progression-free survival in many solid malignancies …
antiangiogenic activity and improves progression-free survival in many solid malignancies …
VEGF-A121 assay
N Papadopoulos, D Anthony, D MacDonald - US Patent 9,116,159, 2015 - Google Patents
The invention provides a method for determining the level of VEGF-A 121 isoform in a
sample by selectively removing the VEGF-A 165 isoform from the sample using a neuropilin …
sample by selectively removing the VEGF-A 165 isoform from the sample using a neuropilin …
VEGF-A 121 assay
N Papadopoulos, A Dore, D Macdonald - 2015 - freepatentsonline.com
The invention provides a method for enriching the level of VEGF-A 121 isoform in a sample
by selectively removing the VEGF-A 165 isoform from the sample using a neuropilin-1 pull …
by selectively removing the VEGF-A 165 isoform from the sample using a neuropilin-1 pull …
VEGF-A121 assay
N Papadopoulos, D Anthony, D MacDonald - US Patent 9,459,263, 2016 - Google Patents
The invention provides a method for enriching the level of VEGF-A isoform in a sample by
selectively removing the VEGF-Ass isoform from the sample using a neuropilin-1 pull-down …
selectively removing the VEGF-Ass isoform from the sample using a neuropilin-1 pull-down …
Anti-Angiogenesis Therapy in Melanoma
DS Chen - Targeted Therapeutics in Melanoma, 2012 - Springer
Malignant melanoma is a highly vascular tumor that tends to grow rapidly and metastasize
aggressively. The formation of new tumor vasculature (angiogenesis) and lymphatics …
aggressively. The formation of new tumor vasculature (angiogenesis) and lymphatics …