Generation of nanoscopic membrane curvature for membrane trafficking

MM Kozlov, JW Taraska - Nature reviews Molecular cell biology, 2023 - nature.com
Curved membranes are key features of intracellular organelles, and their generation
involves dynamic protein complexes. Here we describe the fundamental mechanisms such …

Structural diversity within the endoplasmic reticulum—from the microscale to the nanoscale

CJ Obara, AS Moore… - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
The endoplasmic reticulum (ER) is a continuous, highly dynamic membrane compartment
that is crucial for numerous basic cellular functions. The ER stretches from the nuclear …

Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER

J Nixon-Abell, CJ Obara, AV Weigel, D Li, WR Legant… - Science, 2016 - science.org
INTRODUCTION The endoplasmic reticulum (ER) is a continuous, membrane-bound
organelle, spanning from the nuclear envelope to the outer cell periphery, that contacts and …

Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function

W Jang, D Puchkov, P Samsó, YT Liang… - Science, 2022 - science.org
Cells respond to fluctuating nutrient supply by adaptive changes in organelle dynamics and
in metabolism. How such changes are orchestrated on a cell-wide scale is unknown. We …

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network

S Wang, H Tukachinsky, FB Romano, TA Rapoport - elife, 2016 - elifesciences.org
In higher eukaryotes, the endoplasmic reticulum (ER) contains a network of membrane
tubules, which transitions into sheets during mitosis. Network formation involves curvature …

[HTML][HTML] APEX fingerprinting reveals the subcellular localization of proteins of interest

SY Lee, MG Kang, JS Park, G Lee, AY Ting, HW Rhee - Cell reports, 2016 - cell.com
Deciphering the sub-compartmental location of a given protein of interest may help explain
its physiological function, but it can be challenging to do using optical or biochemical …

Intertwined and finely balanced: endoplasmic reticulum morphology, dynamics, function, and diseases

HT Perkins, V Allan - Cells, 2021 - mdpi.com
The endoplasmic reticulum (ER) is an organelle that is responsible for many essential
subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like …

A role for endoplasmic reticulum dynamics in the cellular distribution of microtubules

MS Tikhomirova, A Kadosh… - Proceedings of the …, 2022 - National Acad Sciences
The dynamic distribution of the microtubule (MT) cytoskeleton is crucial for the shape,
motility, and internal organization of eukaryotic cells. However, the basic principles that …

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling

P Zheng, Q Chen, X Tian, N Qian, P Chai, B Liu, J Hu… - Cell research, 2018 - nature.com
The endoplasmic reticulum (ER) is composed of the nuclear envelope, perinuclear sheets
and a peripheral tubular network. The peripheral ER and mitochondria form tight contacts at …

A glossary of plant cell structures: current insights and future questions

BH Kang, CT Anderson, S Arimura, E Bayer… - The Plant …, 2022 - academic.oup.com
In this glossary of plant cell structures, we asked experts to summarize a present-day view of
plant organelles and structures, including a discussion of outstanding questions. In the …