Many phytochemicals with beneficial physiological activities have limited bioavailability due
to their poor solubility and stability characteristics. The bioactivities of phytochemicals could …

Human serum albumin (HSA) is an abundant plasma protein, which attracts great interest in
the pharmaceutical industry since it can bind a remarkable variety of drugs impacting their …

A biologically active antibacterial reagent, 2–amino-6-hydroxy–4–(4-N, N-
dimethylaminophenyl)-pyrimidine-5-carbonitrile (AHDMAPPC), was synthesized. It was …

Human serum albumin (HSA) is an abundant plasma protein that binds a remarkably wide
range of drugs, thereby restricting their free, active concentrations. The problem of …

Glycation involves the non-enzymatic addition of reducing sugars and/or their reactive
degradation products to amine groups on proteins. This process is promoted by the …

All properties of organic moleculessphysical, chemical, biological, and
technologicalsdepend on their chemical structure and vary with it in a systematic way. The …

Nominal effect concentrations from in vitro toxicity assays may lead to inaccurate estimations
of in vivo toxic doses because the nominal concentration poorly reflects the concentration at …

Taxanes are standard treatment for metastatic breast cancer; however, the solvents used as
vehicles in these formulations cause severe toxicities. The FDA recently approved a solvent …

Subdomain IIA binding site of human serum albumin (HSA) was characterized by examining
the change in HSA fluorescence in the native, unfolded, and refolded states. The study was …

Human serum albumin (HSA) is an abundant and highly soluble plasma protein with the
capacity to bind a remarkably diverse set of lipophilic anionic compounds so that it fulfils …