[HTML][HTML] Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies

G Zhu, X Wang, L Chen, C Lenahan, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal

A Ayala, MF Muñoz, S Argüelles - Oxidative medicine and …, 2014 - Wiley Online Library
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

[HTML][HTML] Reactive oxygen species in inflammation and tissue injury

SM Rizwan, P ReddySekhar… - Antioxidants & redox …, 2014 - liebertpub.com
Reactive oxygen species (ROS) are key signaling molecules that play an important role in
the progression of inflammatory disorders. An enhanced ROS generation by …

[HTML][HTML] New insights into the mechanisms of pulmonary edema in acute lung injury

R Herrero, G Sanchez, JA Lorente - Annals of Translational …, 2018 - ncbi.nlm.nih.gov
Appearance of alveolar protein-rich edema is an early event in the development of acute
respiratory distress syndrome (ARDS). Alveolar edema in ARDS results from a significant …

Cell-based biosensors and their application in biomedicine

Q Liu, C Wu, H Cai, N Hu, J Zhou, P Wang - Chemical reviews, 2014 - ACS Publications
A biosensor is an analytical device that can be used for detecting analytes and combines a
biological component with a physicochemical detecting transducer. In recent years …

Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities

Z Huang, Z Zhang, C Zhou, L Liu, C Huang - MedComm, 2022 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …

Oxidative stress and neurotoxicity

LM Sayre, G Perry, MA Smith - Chemical research in toxicology, 2008 - ACS Publications
There is increasing awareness of the ubiquitous role of oxidative stress in
neurodegenerative disease states. A continuing challenge is to be able to distinguish …

[HTML][HTML] Crosstalk of tight junction components with signaling pathways

L González-Mariscal, R Tapia, D Chamorro - Biochimica et Biophysica Acta …, 2008 - Elsevier
Tight junctions (TJs) regulate the passage of ions and molecules through the paracellular
pathway in epithelial and endothelial cells. TJs are highly dynamic structures whose degree …

Brain endothelial cell-cell junctions: how to “open” the blood brain barrier

SM Stamatovic, RF Keep… - Current …, 2008 - ingentaconnect.com
The blood-brain barrier (BBB) is a highly specialized structural and biochemical barrier that
regulates the entry of blood-borne molecules into brain, and preserves ionic homeostasis …

Redox control of microglial function: molecular mechanisms and functional significance

AI Rojo, G McBean, M Cindric, J Egea… - Antioxidants & redox …, 2014 - liebertpub.com
Neurodegenerative diseases are characterized by chronic microglial over-activation and
oxidative stress. It is now beginning to be recognized that reactive oxygen species (ROS) …